IsiXhosa - Treatment Action Campaign

kwaye kwangena i-tenofovir endaeni ye-d4T
kwiminyaka emininzi eyadlulayo.
Amalingo ezonyango abonise okuhle nge-tenofovir
ukodlula i-d4T. Uphononongo obeluthiwe thaca
kwiNkonfa yoMbutho wamaZwe ngamaZwe we-
AIDSA (International AIDS Society Conference)
ngo-2009 eKapa lwabonisa ukuba iirejimeni
eziqulethe i-d4T zineziphumo ebezingalindelekanga
ezimandundu ezininzi kwaye zifune utshintsho
lwamachiza rhoqo kuneerejimeni eziqulethe
i-tenofovir. Uphononongo lwaluthelekisa izigulane
ezili-1000 ezazikwirejimeni equlethe i-tenofovir
kwi-1000 yezigulane ngenye indlela ezazikwirejimeni
efanayo kodwa yona equlethe i-d4T. I-50.5%
oyezigulane ezithatha i-d4T yehlelwa ziziphumo
ebezingalindelekanga ezinxulumene ne-d4T yaze
i-16.2% yathsintshelwa kwichiza elitsha ekupheleni
kweminyaka emibini. Kwiqela le-tenofovir
yi-2.5% kuphela yezigulane eyehlelwa sisiphumo
esinxulumene ne- tenofovir.
Ezinye zeziphumo ebezingalindelekanga
ezinxulunyaniswa ne-d4T ziquka i-lactic acidosis
(imelo apho i-lactic acid yakheka ngokukhawuleza
egazini kunokuba umzimba uyisuse), i-lipodystrophy
(utshintsho kumafutha omzimba kunye nemilo
yomzimba), i-peripheral neuropathy (umonakalo
kumxokomezelo wemithambo-luvo ye-peripheral)
kunye ne-pancreatitis (ukukrala kwe-pancreas,
ilungu elikhupha iihomoni eziyimfuneko).
Ngokuchaseneyo, izigulane ezikwi-tenofovir
zehlelwa ziziphumo ebezingalindelekanga
ezimandundu ezimbalwa kakhulu. Koko i-tenofovir
iye yanxulunyaniswa nomonakalo wezintso kwaye
izigulane ezithatha ichiza kufuneka zihlolelwe
iingxaki zezintso.
Izikhokelo ezitsha
Iindaba ezimnandi kukuba ukusukela ngomhla
woku-1 Aprili 2010 iSebe lezeMpilo liqalile
ukutshintsha i-d4T nge-tenofovir njengenxenye
yonyango lomgca wokuqala kwiNkqubo yezeMpilo
yoMzntsi Afrika.
Oku akuthethi ukuba wonke umntu okwi-d4T
uyakutshintshela kwi-tenofovir ngoko nangoko.
Kuphela ngabantu abaqala unyango okokuqala
emva komhla we-1 Aprili kunye nabantu abehlelwa
ziziphumo ebezingalindelekanga ezimandundu
kwi- d4T abaza kufumana i-tenofovir. Ukuba
ngaba ukwirejimeni yonyango oluqulethe i-d4T
kwaye awehlelwa zizo naziphi na iziphumo
ebezingalindelekaga, akuyi kubakho mfuneko
yokutshintshela kwi-tenofovir.
Esinye isizathu sokungatshintsheli zonke izigulane
kwi-tenofovir ngexesha elinye, kukuba urhulumente
usenokungakwazi ukufumana i-tenofovir eyoneleyo
yomntu wonke. Kwakhona, ukuba ngaba abantu
baqhuba kakuhle kwi-d4T, asikho isizathu sokuba
bayitshintshe irejimeni yabo.
Imithombo: S. Rosen et al.,
‘Net cost of switching from
stavudine to tenofovir in first
line antiretroviral therapy in
Zambia’, IAS 2009. Available at
http://www.ias2009.org/abstract.
aspx?elementId=200721757.
I-TAC imele ukukhutshwa kwe-tenofovir njengenxenye yeMithombo yephulo leMpilo. Ifoto ngu-Zethu
Mlobeli, courtesy MSF.
I-Tenofovir nethenda ka-2010
ISebe lezeMpilo liwathenga amachiza e-antiretroviral (ARV) ngethenda ye-ARV
ekhethekileyo. Ithenda ye-ARV eyanikwayo ngo-2008 iyaphela kulo nyaka
kwaye urhulumente uzakunika ithenda entsha msinyane nje.
Ukufumana ilungelo lethenda kubalulekile ekuhlangabezaneni nokujoliswe
kuko kwe- NSP, ekuphumezeni izikhokelo ezintsha zonyango kunye nokwehlisa
amaxabiso amachiza. Ngexesha lonke lethenda yonyaka ophelileyo kuphela
yinguqulelo enye kuphela kasinga chiza (generic) tenofovir eyabhaliswayo yaze
yathengiswa. Oku kwathetha ukuba i-tenofovir yahlala ibiza imali eninzi.
Iinguqulelo zoosinga tenofovir ezisalindele ukuba zibhaliswe kwiBhunga
eliLawula amaYeza loMzantsi Afrika (Medicines Control Council) (MCC)
kufuneka zibhaliswe ukonyusa ukhuphiswano kunye nokwehlisa amaxabiso.
Ukuphucula kunye nowenza lula iirejimeni zamachiza i-MCC kufuneka
ikhawulezise ubhaliso lwazo zonke iindibaniselwano ze-tenofovir ezisekelwe
kwidosi esisigxiba.
Jonga kwiphepha le-12 ngokuthe vetshe ngethenda ka-2010 ye-ARV kunye
nemiqobo kwi-MCC.
IZIKHOKELO EZINTSHA
NETHENDA
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