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Principles of Animal Physiology

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<strong>Principles</strong> <strong>of</strong> <strong>Animal</strong> <strong>Physiology</strong><br />

Respiratory System<br />

Control <strong>of</strong> Respiration<br />

▪ Central Chemoreceptors<br />

▸ Mediate response by changes in PCO 2 and H +<br />

▸ Arterial PCO 2 crosses BBB → CSF PCO 2<br />

▸ In CSF: CO2 + H2O → H + + HCO -<br />

3<br />

▸ H + ▸ H causes ↑ ventilation<br />

* H + ▸ * H d tdiff BBB<br />

+ do not diffuse across BBB

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