The Oxford Thesaurus An A-Z Dictionary of Synonyms INTRO ...

take up with the mayor. 4 Usually, major issue. (major or big)
problem or difficulty, controversy, fight, dispute, cause
c‚lŠbre: He turns even walking the dog into a major issue. 5
printing, edition, version; copy, number: I have a copy of the
Sunday issue. See if you can buy an issue of today's paper. 6
publication, promulgation, issuance, issuing, distribution,
delivery, dissemination, broadcasting, proclamation,
circulation: There will be a special issue of stamps to
commemorate his death. 7 offspring, child or children,
descendant(s), progeny, young, scion(s), son(s), daughter(s):
According to the records, your uncle died without issue, making
you his sole heir. 8 at issue. in contention, in dispute,
unresolved, unsettled, uncertain, up in the air, to be decided:
The point at issue is which system will be the most efficient.
9 take issue. disagree, argue, contend, dispute, oppose, take
exception: I feel that I must take issue with your conclusion.
--v. 10 proclaim, promulgate, declare, publish, put out, put or
set forth, announce, circulate, distribute, get out, release,
deliver, broadcast, disseminate, get out: The kidnappers have
issued an ultimatum. 11 emerge, come or go forth, exit,
emanate, discharge, stream, flow, pour; appear, originate,
spring, stem, arise: The play ended, and people issued from the
theatre. Where Pegasus stamped his foot the Pierian spring
issued forth.
9.9 itch...
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itch v. 1 tickle, tingle, prickle: These mosquito bites itch
terribly. 2 desire, crave, hanker, hunger, thirst, yearn, pine,
wish, want, die: I am itching to get my hands on whoever told
you that I was dead.
--n. 3 tickle, tickling, tingle, tingling, prickle, prickling,
irritation: My frustration is like having an itch I can't
scratch. 4 desire, craving, hankering, hunger, thirst,
yearning, longing, Colloq yen: I have a sudden itch to visit
mother for the weekend.
item n. 1 detail, article, point, particular, matter, thing,
element, component, ingredient: There's one item I'd like you