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An overview of sexually transmitted diseases. Part III ... - Dermatology

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Directions for questions 1-16: Give single best response.<br />

1. A patient with AIDS comes to your clinic with her first<br />

case <strong>of</strong> genital herpes. A good estimate <strong>of</strong> the likelihood<br />

that her infection will be resistant to acyclovir is<br />

a. less than 1%<br />

b. 3%<br />

c. 6%<br />

d. 12%<br />

e. 24%<br />

2. A patient comes to your clinic with AIDS and a history<br />

<strong>of</strong> anal warts. Each <strong>of</strong> the following is true except<br />

a. patients with AIDS generally have more human<br />

papillomavirus (HPV) subtypes present in their<br />

infections.<br />

b. as his CD4 cell counts drop, this patient will shed<br />

more HPV virions.<br />

c. concurrent HIV and anal HPV infections increase<br />

this patient’s risk for anorectal carcinoma.<br />

d. optimizing his antiretroviral medications may<br />

make management <strong>of</strong> any anal wart recurrences<br />

more feasible.<br />

d. acetic acid is not a useful diagnostic tool for recognizing<br />

anal squamous intraepithelial lesions in this<br />

patient.<br />

3. Kaposi’s sarcoma (KS)<br />

a. is not associated with human herpesvirus type 8 in<br />

HIV-infected patients<br />

b. is associated with an increased risk for non-<br />

Hodgkin’s lymphoma in HIV-infected patients<br />

c. occurs most commonly among people who<br />

acquired HIV through intravenous drug abuse<br />

d. occurs at similar rates for HIV-infected patients in<br />

all US cities<br />

e. does not follow the epidemiologic patterns <strong>of</strong> an<br />

infectious disease<br />

4. The best approximation for the number <strong>of</strong> scabies<br />

mites on an HIV-infected patient with crusted scabies<br />

is<br />

a. fewer than 5<br />

b. 5-10<br />

c. 10-20<br />

d. 20-50<br />

e. more than 50<br />

5. In the treatment <strong>of</strong> AIDS patients with crusted scabies,<br />

which <strong>of</strong> the following medications has been<br />

CME examination<br />

Identification No. 800-109<br />

Instructions for Category I CME credit appear in the front advertising section. See last page <strong>of</strong> Contents for page number.<br />

Questions 1-31, Czelusta A, Yen-Moore A, Tyring SK. J Am Acad Dermatol 2000;43:409-32.<br />

documented as a potential cause <strong>of</strong> severe neurologic<br />

side effects in case reports?<br />

a. Lindane<br />

b. Permethrin<br />

c. Mebendazole<br />

d. Metronidazole<br />

e. Ivermectin<br />

6. The most likely mechanisms by which herpes simplex<br />

virus (HSV) mediates resistance to thymidine kinase<br />

inhibitors includes each <strong>of</strong> the following except<br />

a. production <strong>of</strong> viral thymidine kinase with decreased<br />

substrate affinity<br />

b. production <strong>of</strong> viral DNA polymerase with decreased<br />

substrate affinity<br />

c. decreased production <strong>of</strong> viral thymidine kinase<br />

d. absence <strong>of</strong> viral thymidine kinase production<br />

e. altered transport <strong>of</strong> thymidine kinase inhibitors<br />

into infected cells<br />

7. <strong>An</strong> HIV-infected patient who is allergic to penicillin<br />

comes to your clinic with early latent syphilis. Which<br />

<strong>of</strong> the following antibiotics is the most appropriate<br />

therapy?<br />

a. Intramuscular benzathine penicillin G<br />

b. Oral cipr<strong>of</strong>loxacin<br />

c. Oral erythromycin<br />

d. Intravenous vancomycin<br />

e. Intramuscular ceftriaxone<br />

8. Chancroid in HIV-positive patients<br />

a. is commonly atypical in its clinical presentation<br />

b. presents with larger ulcers than those seen in HIVnegative<br />

patients<br />

c. has distinct histologic differences from HIV-negative<br />

patients on microscopic examination<br />

d. increases the risk <strong>of</strong> HIV transmission to sexual<br />

partners<br />

e. cannot be cured by the same antibiotic regimens<br />

that are recommended for immunocompetent<br />

patients<br />

9. A patient with advanced AIDS presents with a facial<br />

molluscum contagiosum. Which <strong>of</strong> the following<br />

should he be told about the lesion?<br />

a. Shaving his face will help improve skin cleanliness<br />

and decrease the likelihood <strong>of</strong> new lesions developing.<br />

b. Optimization <strong>of</strong> his antiretroviral medications will<br />

not help in the care <strong>of</strong> this lesion.<br />

433

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