An overview of sexually transmitted diseases. Part III ... - Dermatology

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434 CME examination J AM ACAD DERMATOL SEPTEMBER 2000 c. Crude podophyllin resin is the safest therapeutic modality for the removal of this lesion. d. This infection is unlikely to resolve spontaneously. e. Carbon dioxide laser therapy is the most efficacious modality for treating this lesion. 10. Each of the following statements regarding syphilis in the HIV-infected host is true except a. Clinical presentation is usually the same in HIVinfected persons as it is in HIV-negative hosts. b. Several studies document increased rates of falsepositive fluorescent treponemal antibody absorption assays. c. A patient’s progression through the various stages of syphilis may be faster if he is HIV infected. d. HIV-infected patients may progress to neurosyphilis despite treatment with recommended antibiotic regimens. e. Histologic examination of tissue specimens may be helpful in cases in which the results of HIV-infected patients’ serologic tests are not consistent with their dermatologists’ clinical suspicions. 11. Which of the following statements is false? a. Patients with genital herpes are at increased risk of acquiring HIV from their HIV-positive partners. b. Antiviral control of HSV has no impact on a patient’s response to antiretroviral drugs. c. Treatment of genital herpes in HIV-positive persons may require increased doses of acyclovir or famciclovir. d. A person with both HSV and HIV infections has an increased risk of transmitting HIV relative to an HSV-negative person with HIV. e. Taking famciclovir daily reduces both symptomatic and asymptomatic HSV viral shedding in HIV-positive persons. 12. Which of the following is the most common cause of genital ulcer disease worldwide? a. HIV b. Chancroid c. Herpes d. Lymphogranuloma venereum e. Granuloma inguinale 13. Which of the following drugs is most likely to benefit a patient with acyclovir-resistant herpes? a. Cidofovir b. Famciclovir c. Valacyclovir d. Penciclovir e. Zidovudine 14. Which of the following is least likely to mimic molluscum contagiosum in an HIV-positive person? a. Cryptococcus b. Penicillium marneffei c. Histoplasmosis d. Condyloma acuminatum e. Granuloma inguinale 15. Which of the following statements is false? a. Anal cancer is the most common reportable cancer among HIV-positive men. b. Anal cancer is 7 times more common in homosexual men with HIV than those who are HIV seronegative. c. Cervical cancer in an HIV-infected patient is an AIDS-defining illness. d. Condyloma acuminatum in an HIV-positive person may contain dysplastic foci. e. Crude podophyllin resin contains mutagens. 16. What effect has highly active antiretroviral therapy had on KS? a. KS is more treatment resistant. b. KS is less prevalent. c. KS is more frequently seen in HIV-positive women. d. KS is more frequently seen in hemophiliacs e. KS is more likely to be the immediate cause of death in HIV-positive persons. Directions for questions 17-21: For each numbered item, choose the appropriate lettered item. a. Hepatitis C virus b. Human papillomavirus type 16 c. Chancroid d. Molluscum contagiosum virus 1 e. Molluscum contagiosum virus 2 17. Children 18. Porphyria cutanea tarda 19. Anal cancer 20. Genital ulcers in Africa 21. Facial papules in HIV-positive adults Directions for question 22: Give single best response. 22. Which of the following statements is true? a. Scabies are proven to transmit HIV. b. KS in HIV-negative persons is not associated with human herpesvirus type 8. c. High recurrence rates of molluscum contagiosum are usually due to reinfection. d. HIV can frequently be found in herpetic ulcers of HIV-positive persons. e. Acyclovir has direct antiretroviral activity. Directions for questions 23-27: For each numbered item, choose the appropriate lettered item. a. Foscarnet b. Cidofovir c. Famciclovir d. Imiquimod e. Azithromycin 23. May be useful topical therapy for warts and molluscum contagiosum (also available in a topical formulation) 24. Requires thymidine kinase for activation
J AM ACAD DERMATOL VOLUME 43, NUMBER 3 25. Approved by the Centers for Disease Control and Prevention (CDC) in intravenous form for acyclovirresistant herpes 26. Nucleotide analog 27. Recommended by the CDC for therapy of chancroid in HIV-positive persons Directions for questions 28-31: Give single best response. 28. What is the approximate relative increase in risk of HIV transmission from having a sexually transmitted disease? a. 1- to 2-fold b. 3- to 5-fold c. 6- to 10-fold d. 11- to 20-fold e. 21- to 50-fold 29. Which statement is false regarding herpetic ulcers in HIV-positive persons? a. Hyperkeratotic verrucous lesions may resemble condyloma acuminatum. b. Higher doses of antiherpes agents may be required. c. Ulcers may be coinfected with cytomegalovirus. d. Therapy may prevent visceral spread of HSV. e. Foscarnet therapy has the same safety profile as acyclovir. AVAILABILITY OF JOURNAL BACK ISSUES CME examination 435 30. Which statement is true regarding scabies in HIV-positive persons? a. Mites are difficult to detect. b. Crusted lesions are more pruritic than papular lesions. c. Papular and crusted lesions are not mutually exclusive. d. Crusted scabies is clearly distinguishable clinically from eczema. e. Plaques of crusted scabies rarely fissure. 31. Which statement is false regarding granuloma inguinale in HIV-positive persons? a. It is strongly associated with HIV transmission. b. CDC-recommended treatment of granuloma inguinale is different than in HIV-negative persons. c. The mean duration of ulcer healing may be longer in HIV-positive persons. d. Greater tissue destruction may be seen in HIV-positive persons. e. Extragenital dissemination has been reported in HIV-positive persons. As a service to our subscribers, copies of back issues of the Journal of the American Academy of Dermatology for the preceding 5 years are maintained and are available for purchase from Mosby until inventory is depleted. The following quantity discounts are available: 25% off on quantities of 12 to 23, and one third off on quantities of 24 or more. Please write to Mosby, Subscription Customer Service, 6277 Sea Harbor Dr, Orlando, FL 32887, or call 800-654-2452 or 407-345-4000 for information on availability of particular issues and prices. If unavailable from the publisher, photocopies of complete issues may be purchased from Bell & Howell Information and Learning, 300 N Zeeb Rd, Ann Arbor, MI 48106, (313)761-4700.
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