Neonatal Jaundice: When Do the Light Bulbs Go On? - Trinity Health

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Phototherapy for Neonatal Hyperbilirubinemia • Effectively reduces indirect (unconjugated) bilirubin levels and has dramatically reduced need for exchange transfusions; 30-40% decline in 24 hours • “Pumps” bilirubin (converts to structural and configurational photoisomers) from skin-”bleaches” skin – Degradation products more easily excreted in urine, bile • Transcutaneous bilirubin (TcB), Visual inspection: NEITHER RELIABLE UNDER PHOTOTHERAPY • Total Serum Bilirubin (TSB) Levels-Laboratory – Indirect equals total serum bilirubin (TSB) level unless direct over 20% of TSB level >5 mg/dL – Note: Direct bilirubin may reduce albumin binding capacity
Factors Related to Efficacy of Phototherapy Maisels MJ, Mcdonagh AF. N Engl J Med 2008; 358:920-928
Page 1: Perinatal Symposium--2012 “Neonat
Page 4 and 5: Neonatal Hyperbilirubinemia • Pat
Page 7 and 8: Neonatal Indirect-Unconjugated Hype
Page 9 and 10: Neonatal Hyperbilirubinemia Bilirub
Page 11 and 12: Neonatal Hyperbilirubinemia • Gen
Page 13 and 14: Neonatal Hyperbilirubminemia TSB LE
Page 15 and 16: Important Risk Factors-Significant
Page 17 and 18: Breastfeeding versus Breast Milk Ja
Page 19 and 20: Adequacy of Breast Feeding • Adeq
Page 21 and 22: Neonatal Hyperbilirubinemia: ABO In
Page 23 and 24: » EVALUATION-NEONATAL JAUNDICE
Page 25 and 26: 2 3 1 4 5 Neonatal Jaundice Dermal
Page 27 and 28: Neonatal Hyperbilirubinemia-Patholo
Page 29 and 30: Additional Evaluation of Neonatal H
Page 31 and 32: Monitoring with Transcutaneous Bili
Page 33 and 34: Transcutaneous Bilirubinometry Scre
Page 35 and 36: Common Causes of Prolonged (3 weeks
Page 37 and 38: Neonatal Hyperbilirubinemia • Pat
Page 39: Maisels MJ, Mcdonagh AF. Mechanism
Page 43 and 44: Mangement Under Phototherapy (Conti
Page 45 and 46: Bili Tool • Risk for development
Page 47 and 48: Phototherapy-Hospital, Home • Bil
Page 49 and 50: PREVENTION - SEVERE HYPERBILIRUBINE
Page 51 and 52: Patient 2 (Continued) In the ER, th
Page 53 and 54: Kernicterus • Can occur in health
Page 55 and 56: Kernicterus • Can NOT associate a
Page 57 and 58: Predictive Ability of a Pre Dischar
Page 59 and 60: Predischarge Risk Zone Bilirubin Le
Page 61 and 62: Hyperbilirubinemia in the Newborn I
Page 63 and 64: Commentary on Hyperbilirubinemia in
Page 65 and 66: Screening of Infants for Hyperbilir
Page 67 and 68: » SUMMARY
Page 69 and 70: Ten Key Recommendations for Prevent
Page 71 and 72: Maroon and Gold Summary Points •
Page 74 and 75: References: General American Academ
Page 76 and 77: References: Breast Feeding de Almei
Page 78 and 79: References Bilirubin Predischarge S
Page 80: References: Kernicterus Davidson L,

Neonatal Jaundice: When Do the Light Bulbs Go On? - Trinity Health

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