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Neonatal Jaundice: When Do the Light Bulbs Go On? - Trinity Health

Neonatal Jaundice: When Do the Light Bulbs Go On? - Trinity Health

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<strong>Neonatal</strong> Hyperbilirubinemia-Bilirubin<br />

Encephalopathy* (2008)<br />

• Major neurotoxicity risk factors<br />

– Rh Isoimmunization<br />

• (NOT ABO incompatibility)<br />

– Sepsis<br />

– Prematurity<br />

• No Risk Factors<br />

*34-36 weeks Gestational Age<br />

TSB ≥ 25mg/dL<br />

TSB ≥ 30-31 mg/dL<br />

Note: Biological factors besides bilirubin level are important in<br />

pathogenesis of bilirubin encephalopathy<br />

From Gamaleidin, R etal<br />

Pediatrics 2011; 128;e925-e931

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