MEDICINAL CHEMISTRY

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3. D. A. Williams and T. l. Lemke, Foye’s Principles of Medicinal Chemistry, 5 th edition, Lippincott Williams & Wilkins, Philadelphia, 2002. 4. D. Lednicer and L.A. Mitscher: An Organic Chemistry of Drug Synthesis Vol. II, & III, John Wiley and Sons, New York, 1980, 1984 5. S. N. Pandeya: A Textbook of Medicinal Chemistry, Vol-1, S.G. Publishers, Varanasi, 2003. 6. Ashutosh Kar, Medicinal Chemistry, 3 rd edition, Wiley Eastern, Ltd, New Delhi,2005. 7. I. L. Finar: Organic Chemistry Vol. 1 & 2. The English Language Book Society, London, 1977. 8. S.S. Kadam, K.R. Mahadik & K.G. Bothara: Principles of Medicinal Chemistry Vol. I & II, Nirali Prakashan, Pune, 2003. 9. Pharmacopoeia of India, Govt. of India. Ministry of Health, Delhi, 2001. 10. Harkishan Singh and V. K. Kapoor, Medicinal and Pharmaceutical Chemistry, Vallabh Prakashan, 2005.
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CONTENTS Antianginal Drugs Anticoag
Page 3 and 4:
c) Dihydropyridine derivative: e.g.
Page 5 and 6:
2 (d) 4. H 3C H 3C HO CH-CH 2-O-CH
Page 7 and 8:
pentaerythritol, and is supplied di
Page 9 and 10:
of' streptokinase, urokinase and ti
Page 11 and 12:
Low-molecular-weight Heparins, B.P.
Page 13 and 14:
OH COOCH 3 AC 2O Methyl salicylate
Page 15 and 16:
Warfarin and other coumarin derivat
Page 17 and 18:
Structure-activity Relationship All
Page 19 and 20:
Mean Arterial Blood Pressure (MABP)
Page 21 and 22:
Table-1 ---------------------------
Page 23 and 24:
Ramipril Altace ( Hoechst-Marion) 2
Page 25 and 26:
Official drugs: Prazosin Hydrochlor
Page 27 and 28: treatment of hypertension, the dosa
Page 29 and 30: NH ClCH 2CN NCH 2CN Perhydroazocine
Page 31 and 32: B (2). Angiotensin Receptor Antagon
Page 33 and 34: CH3COOC2H5 Diazoxide (90) Cl NH 2 S
Page 35 and 36: Structure-activity Relationships of
Page 37 and 38: N N R Acidic group (102) Acidic gro
Page 39 and 40: Structure-activity Relationships of
Page 41 and 42: HO HO HO HO H 3C CH 3 H Digitoxigen
Page 43 and 44: efractory periods. These are mainly
Page 45 and 46: Structure - Activity Relationship:
Page 47 and 48: Hydralazine is a direct relaxant of
Page 49 and 50: K4[Fe(CN) 6].3H2O + 6HNO3 H2[(NO)Fe
Page 51 and 52: conduction velocity, and decrease s
Page 53 and 54: Synthesis of Moricizine: (153) H N
Page 55 and 56: Tocainide Hydrochloride (±)-2-Amin
Page 57 and 58: influx through β-receptor blockade
Page 59 and 60: Cl Cl CH2CH=CH2 N N N H Alinidine (
Page 61 and 62: (iii) Intermediate density lipoprot
Page 63 and 64: Structure-activity Relationship Mev
Page 65 and 66: to the bile acids. Thus due to ente
Page 67 and 68: moderate reduction in cholesterol l
Page 69 and 70: (iii) Other types: (a) Insulin rece
Page 71 and 72: non-crystalline insulin as far as o
Page 73 and 74: for better drug in this series. Sub
Page 75 and 76: Key to general structure X SO 2 NH
Page 77: Official Drugs: Insulin, B.P. It is
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MEDICINAL CHEMISTRY

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