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initial characterization of crude extracts from phyllanthus amarus

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Origin and Distribution<br />

Plants in the genus Phyllanthus can be found around all tropical regions <strong>of</strong> the<br />

world: <strong>from</strong> Africa to Asia, South America and the West Indies. Phyllanthus contains<br />

about 550 to 750 species in 10-11 subgenera (Unander, 1995).<br />

P. <strong>amarus</strong> can be found in all the tropical regions <strong>of</strong> the world: through the roads,<br />

valleys, on the riverbanks and near lakes. This plant is a common arable weed <strong>of</strong><br />

disturbed ground in southern Florida, the Bahamas, the West Indies and tropical America<br />

and is naturalized in the Old World tropics. Phyllanthus <strong>amarus</strong> is usually misidentified<br />

with the closely related Phyllanthus niruri L. in appearance, phytochemical structure and<br />

history <strong>of</strong> use. Phyllanthus niruri reaches a length <strong>of</strong> 60 cm, the fruits are larger, and the<br />

seeds are dark brown and warty (Morton, 1981).<br />

Use<br />

Many Euphorbiaceae species are <strong>of</strong> economical importance. For example, the<br />

cooked root <strong>of</strong> Manihot esculenta (cassava) is used as a major carbohydrate source in the<br />

tropics, and many forms <strong>of</strong> bread and puddings are made <strong>of</strong> the starch. From the oily<br />

seeds <strong>of</strong> Ricinus communis (krapata), miracle oil is produced. Many species are more or<br />

less poisonous (Morton, 1981; Wessels Boer, 1976). According to Lewis (1977) the<br />

milky sap <strong>of</strong> many cultivated species, such as E. pulcherrima (pointsettia) and E.<br />

tirucallii (pencil tree) contains toxic compounds that will cause severe poisoning if<br />

ingested in large quantities.<br />

E. pulcherrima is commercially grown as an ornamental in the Americas. E.<br />

tirucallii is widely grown in the warm climates <strong>of</strong> both hemispheres as an ornamental<br />

plant and massive barrier hedge. The latex <strong>of</strong> this plant is a source <strong>of</strong> hydrocarbons and<br />

convertible to fuel. Alchornea latifolia is planted as shade for c<strong>of</strong>fee in Mexico. The<br />

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