REVIEW OF LITERATURE

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15 reverting a similar spasm of jejunum of rabbit and had no relaxing effect alone. When intragastric administration of himachalol or papaverine 100 mg/kg in the conscious immobilized cat was done it produced equal inhibition of carbachol, induced spasm of the intestine, lasting about two hours. Himachalol has faster onsetofaction than papaverine. Himachalol has spasmolytic effect on bronchial muscles of guinea pig but it was 3.3 times more potent than papaverine in antagonizing epinephrine-induced contraction of seminal vesicle of guinea pig. In the cat intravenous administration of Himachalol 3-10 mg/Kg produced a dose dependent fall in blood pressure and an increased femoral blood flow. I Himachalol Alexander and Rao (1975) described preferential addition of CCl4 to limonene gamonoadduct which lost HCl on distillation to give trichlorohyllimonene (I) which was hydrolyzed by alcoholic alkali to 10 carboxylimonene. 4hyl-tetrahydroacetophenone form hydrolysis of I with ethylene glycol (30%) at 200-210 oC with simultaneous steam distillation. H 3C H 3C HO CH 3 CH 3
16 H 3C C Kulshreshtha and Rastogi (1975) described the structure of centdarol on the basis of IR 1 NMR and mass spectra. This is structurally 2β,7β-dihydroxyhimachal-3-ene. (I) Sabine (1975) described their exposure to an environment containing the aromatic red cedar, Juniperus virginiana. It showed procarcinogenic, enzyme-inducing and insecticidal effects. Sabine also described that (i) Shaving from the Eastern Red Cedar (Juniperus virginiana) was performed and effect was examined for three diverse biological properties, i.e. enzyme induction, procarcinogenicity and insecticidal activity. (ii) The ability of a cedar environment to stimulate liver drug-metabolizing enzymes in mice was confirmed by lowered values for barbiturate sleeping time. (iii) In susceptible strains of mice the use of cedar shaving as bedding increased significantly. The incidence of spontaneous tumors of the liver and mammary gland was observed and it also reduced the average time at which tumors appeared. (iv) Cedar and some of its derivatives (oil of cedarwood, cedrene, cedrol) distrupted the reproductive and development cycle of a number of insects, including the Peanut Trash Bug (Elasmolomus CH3 CHCCl 3
Page 1 and 2: 6 REVIEW OF LITERATURE Krishna-Rao
Page 3 and 4: 8 Adinarayana and Seshadri (1965) d
Page 5 and 6: 10 in the un-saponifiable matter. D
Page 7 and 8: 12 whereas Rubia cordifolia, Oroxyl
Page 9: 14 Algar flynn-oyamada fraction yie
Page 13 and 14: 18 Agrawal and Rastogi (1982) descr
Page 15 and 16: 20 properties. They reported biolog
Page 17 and 18: 22 Takigawa et al. (1989) described
Page 19 and 20: 24 found as 20,000, 10,000, 8000 an
Page 21 and 22: 26 membrane of the renal tubular ce
Page 23 and 24: 28 micrograms ml-1) and ITZ (GM.MIC
Page 25 and 26: 30 this study inhibited the develop
Page 27 and 28: 32 molluscicides significantly redu
Page 29 and 30: 34 treatment of the plant-derived m
Page 31 and 32: 36 that such acids could be widespr

REVIEW OF LITERATURE

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