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REVIEW OF LITERATURE

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33<br />

naturally, were sensitized more than patients from distant places. The<br />

immunochemical characterization revealed multiple protein fractions<br />

from low to very high molecular mass (14-126 kDa) mostly in the acidic<br />

pH range. Cedrus deodara pollen has been recognized as a new allergen<br />

from India for the first time. The role of pollen as a causative agent of<br />

respiratory allergic disorders is very well established, as is evident from<br />

the recent increase of reports from across the world. India is blessed<br />

with the richest flora on the earth, from alpine tundra to Rajasthan<br />

desert. Consequently, it provides considerable variation in the quality<br />

and quantity of airborne pollens in different ecogeographic regions of the<br />

country. Although studies on the allergenic properties of airborne<br />

pollens from various species have been carried out by several workers in<br />

India, information on allergy to aerial pollen from Himalayan tree species<br />

has been completely ignored.<br />

Rao and Singh (2001) reported combinations of Azadirachta indica<br />

and Cedrus deodara oil with piperonyl butoxide, MGK-264 and Embelia<br />

ribes against Lymnaea acuminata. The binary and tertiary combinations<br />

of plant-derived molluscicides Azadirachta indica and Cedrus deodara oil<br />

with synergists MGK-264, piperonyl butoxide (PB) and fruit powder of<br />

Embelia ribes were used against the Lymnaea acuminata. It was<br />

observed that the toxic effects of these mixtures were time- and dose-<br />

dependent. The binary and tertiary mixtures of plant-derived<br />

molluscicides with synergists were more toxic with respect to the single

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