download/files/Proteomics brochure 7-08-04.pdf

Ultimate Analytical Flexibility
MDLC LTQ Workstation
Analytical precision
demonstrated by
duplicate analyses
with the MDLC LTQ
8
Relative Abundance
The combination of the Ettan MDLC
chromatography system from GE
Healthcare and the Finnigan LTQ
from Thermo creates a powerful
new integrated LC/MS system
with extraordinary flexibility and
innovative applications.
RT: 0.00 - 60.01
100
90
80
70
60
50
40
30
20
10
0
RT: 0.00 - 60.02
100
90
80
70
60
50
40
30
Relative Abundance
20
10
0
0.10
518.7
5.06
519.0
7.24
535.8
8.60
535.8
11.36
535.8
13.08
518.8
The pumps perform high pressure
mixing and the system uses realtime
flow monitoring to assure
absolute gradient reproducibility.
The entire system flowpath is bioinert,
allowing high-yield analysis
of post-translationally modified
17.67
563.4
17.86
465.6
19.80
501.9
19.77
501.9
20.67
636.8
22.68
536.8
22.73
536.8
25.32
748.3
27.67
616.3
29.29
460.6
31.14
908.5
peptides. The system can perform
rapid LC/MS separations using a
single column or high resolution
multidimensional separations,
allowing customization of separations
for optimal detection of
peptides by the Finnigan LTQ.
34.75
557.6
36.62
518.7
40.34
518.8
42.27
518.7
44.78
518.7
48.53
518.8
MDLC LTQ provides
ultimate versatility
29.28
460.6
0.23
519.0
5.13
535.8
5.41
518.7
7.62
519.0
9.92
518.7
12.90
518.8
16.24
597.4
17.70
465.6
21.53
650.4
25.31
748.3
26.72
771.4
31.04
908.5 34.45
557.7
37.05
789.5
40.38
518.7
0 5 10 15 20 25 30
Time (min)
35 40 45 50 55 60
41.65
518.7
45.26
518.8 45.61
518.8
52.64
783.8
53.00
783.8
53.56
727.3
56.58
518.7
0 5 10 15 20 25 30 35 40 45 50 55 60
Time (min)
49.75
518.8
53.01
462.2
55.93
519.1
57.91
519.1