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Gonioscopic Evaluation of the Anterior Chamber Angle

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<strong>Gonioscopic</strong> <strong>Evaluation</strong> <strong>of</strong> <strong>the</strong><br />

<strong>Anterior</strong> <strong>Chamber</strong> <strong>Angle</strong><br />

University <strong>of</strong> Milan Bicocca<br />

June 2010<br />

Anthony Cavallerano, O.D.<br />

VA Boston Health Care System<br />

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The New England College <strong>of</strong> Optometry<br />

Boston Massachusetts<br />

anthony.cavallerano@va.gov<br />

cavalleranot@neco.edu


GONIOSCOPY<br />

• Gonioscopy is a technique that allows<br />

visualization <strong>of</strong> <strong>the</strong> anterior chamber angle<br />

structures and is used to diagnose abnormalities<br />

<strong>of</strong> <strong>the</strong> anterior segment, in particular <strong>the</strong><br />

anterior chamber angle structures.<br />

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Gonioscopy - Indications<br />

• Glaucoma<br />

– Open angle<br />

– Narrow angle<br />

– Pigmentary/PXF<br />

– Neovascular<br />

• Post Trauma<br />

• Suspiciously marrow angle prior to dilation<br />

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KOEPPE GONIOSCOPY<br />

• Convex lens is placed on anes<strong>the</strong>tized cornea<br />

• Hand held focal illuminator/patient in supine position<br />

• Wide angle view <strong>of</strong> chamber<br />

• Excellent impression <strong>of</strong> iris contour and angle approach<br />

• Low magnification/distorts <strong>the</strong> angle very slightly<br />

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• Koeppe Lens<br />

– Direct Optical system<br />

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Gonioscopy – Koeppe Lens<br />

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INDIRECT GONIOSCOPY<br />

• Zeiss 4 mirror lens<br />

• Goldmann (Universal) mirror lens.<br />

• Slit lamp biomicroscope<br />

• Each quadrant examined indirectly by placing<br />

<strong>the</strong> mirror in <strong>the</strong> quadrant opposite <strong>the</strong> area<br />

to be examined<br />

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• Zeiss 4 mirror lens<br />

– Indirect Optics<br />

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Gonioscopy – Posner lenses<br />

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Gonioscopy – Posner Placement<br />

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Zeiss 4-mirror Zens<br />

• 4 mirrors positioned for gonioscopy<br />

• Central lens for <strong>the</strong> posterior pole<br />

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• Precorneal tear film serves as <strong>the</strong> intervening fluid<br />

• Four angles viewed rapidly<br />

• Central lens provides adequate view <strong>of</strong> posterior<br />

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Indirect Gonioscopy (Contemporary)<br />

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Gonioscopy - Instrumentation<br />

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Gonioscopy – Sussman Lens<br />

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Universal Lens Placement<br />

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<strong>Anterior</strong>-<strong>Chamber</strong> <strong>Angle</strong> Anatomy<br />

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A/C <strong>Angle</strong> and Trabecular Drainage<br />

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Indirect Gonioscopy (Contemporary)<br />

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Gonioscopy - Instrumentation<br />

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Universal/Goldmann Lens<br />

• Most commonly used gonioscopic technique<br />

• Lens eliminates internal reflection redirects image<br />

incorporated in <strong>the</strong> lens<br />

• Requires topical anes<strong>the</strong>tic and intervening fluid<br />

• Monitor corneal epi<strong>the</strong>lium<br />

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Three Mirror Universal (Goldmann) Lens<br />

• Versatile lens<br />

• Larger, easier to handle<br />

• Additional mirrors/lenses<br />

– <strong>Gonioscopic</strong> mirror<br />

– Equatorial and peripheral mirrors<br />

– Central fundus lens for optic disc and macula<br />

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EXAMINATION TECHNIQUES<br />

Goldmann (Univerdsal) lens<br />

• Align slit lamp for patient and examiner<br />

• Low magnification (10x)<br />

• Scan anterior portion <strong>of</strong> eye<br />

• Anes<strong>the</strong>tize cornea<br />

• Fill <strong>the</strong> meniscus <strong>of</strong> <strong>the</strong> lens, halfway with gonioscopic<br />

solution<br />

• Intervening fluid forms strong capillary bonds and allows<br />

moderate lens manipulation<br />

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• Corneal ulcer<br />

Contraindications<br />

• Corneal abrasion<br />

• Blunt or penetrating injury<br />

• New/recent surgical wound<br />

Goldmann tonometry prior to<br />

gonioscopy<br />

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Technique<br />

Insertion<br />

• Set up slit lamp (low mag., narrow beam, straight<br />

ahead)<br />

• Have patient look down, pull upper lid<br />

• Have patient to look up, pull lower lid<br />

• Place lower edge <strong>of</strong> lens in inferior cul-de- sac<br />

• Tilt lens forward against plane <strong>of</strong> cornea, let lower lid<br />

go<br />

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• Position/focus microscope into gonio mirror<br />

• Increase magnification to 16x<br />

• Lens in place - held by capillary action.<br />

– Balance lens without much pressure exerted to globe


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Removal<br />

Technique<br />

• Break suction between lens and cornea<br />

• Irrigate eye with sterile saline<br />

• Clean lens with contact lens cleaning<br />

solution<br />

• Rinse well, air dry and store in container<br />

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STRUCTURAL OVERVIEW TO<br />

UNDERSTANDING GONIOSCOPY<br />

PUPIL AND IRIS:<br />

• pupillary margin<br />

• Iris plane<br />

• Peripheral iris insertion<br />

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Normal angle<br />

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Grading<br />

4 structures = wide open<br />

3 structures<br />

2 questionable<br />

1 = occludable (Schwalbe’s line)<br />

Grading angles<br />

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Normal angle


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CILIARY BODY (CBB)<br />

• Highly vascularized<br />

• <strong>Anterior</strong> iris stroma is continuous over<br />

anterior ciliary body<br />

• Irregular threadlike thickening <strong>of</strong> fibers, called<br />

iris processes branch, coalesce over anterior<br />

ciliary body<br />

• Do not cause increased IOP<br />

• Terminate at scleral spur but occasionally at<br />

Schwalbe's line.<br />

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Scleral Spur<br />

• Easily seen in wide angle at <strong>the</strong> anterior end <strong>of</strong> <strong>the</strong><br />

angle recess where <strong>the</strong> ciliary body inserts.<br />

• Thin white line<br />

• Iris processes stop at this point<br />

• Easily visible when blood fills Schlemm's canal, or<br />

pigment deposited in <strong>the</strong> meshwork.<br />

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SCHLEMM'S CANAL<br />

• Often appears as a gray zone just above scleral spur<br />

• More obvious when blood-filled<br />

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TRABECULAR MESHWORK (TM)<br />

• Trabecular pigment band forms directly in front <strong>of</strong> <strong>the</strong><br />

Schlemm’s canal due to deposition <strong>of</strong> pigment <strong>of</strong> granules<br />

• Denser in pigmentation in brown iris patients than blue eyed<br />

patients<br />

• Band becomes less translucent and more opaque with age<br />

• Inferior angle becomes more pigmented<br />

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SCHWALBE'S LINE<br />

• <strong>Anterior</strong> termination <strong>of</strong> Descemet's membrane<br />

• Represents <strong>the</strong> change in curvature between <strong>the</strong> flat<br />

sclera and steep cornea<br />

• A condensation <strong>of</strong> collagenous fibers which runs<br />

around <strong>the</strong> inner peripheral cornea<br />

• Marks <strong>the</strong> anterior insertion limit <strong>of</strong> <strong>the</strong> angle<br />

structures<br />

• Pigment may be deposited on Schwalbe's line<br />

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SL<br />

TM<br />

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SS<br />

CBB


Abbreviations<br />

• CBB: Ciliary body band<br />

• TM: Trabecular meshwork<br />

• SS: Scleral spur<br />

• SL: Schwalbe’s line<br />

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Recording<br />

• record <strong>the</strong> deepest structure visible in each <strong>of</strong> <strong>the</strong> four<br />

quadrants as shown below (most POSTERIOR structure)<br />

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OD OS


• Recording:<br />

OD OS<br />

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• Classification <strong>of</strong> angle width:


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USE OF GONIOSCOPY<br />

1. Pre -dilation evaluation <strong>of</strong> potentially narrow angles<br />

2. <strong>Evaluation</strong> <strong>of</strong> all potential glaucoma conditions<br />

3. Narrow angle glaucoma<br />

4. Confirmation <strong>of</strong> Primary angle open glaucoma or chronic<br />

open angle glaucoma<br />

5. Secondary open angle glaucoma:<br />

examples:<br />

» Pigmentary dispersion<br />

» Ocular trauma: angle recession<br />

» Lens induced<br />

» Neovascular glaucoma<br />

6. Tumors <strong>of</strong> iris and ciliary body<br />

7. O<strong>the</strong>rs<br />

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Slit Lamp Examination and<br />

• Intact cornea<br />

Tonometry<br />

• <strong>Angle</strong> estimation (temporarily or<br />

nasally)<br />

• Goldmann tonometry<br />

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2. If angle on Van herick are less than 1/4: 1, use <strong>the</strong><br />

gonioscopy lens to evaluate <strong>the</strong> angle.<br />

Van herick:<br />

Width <strong>of</strong> cornea equal to 1<br />

(3/4, 1/2. 1/4, 1/8)<br />

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Width <strong>of</strong> shadow compare to<br />

width <strong>of</strong> cornea in fractions


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3. What is considered a narrow versus open<br />

angle on gonioscopy<br />

OD OS<br />

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Shadow Technique<br />

• Penlight technique: temporally<br />

• If iris is flat, total illumination<br />

• If iris is bowed, shadow forms<br />

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