10.06.2013 Views

http://legacy.library.ucsf.edu/tid/hvk78d00/pdf

http://legacy.library.ucsf.edu/tid/hvk78d00/pdf

http://legacy.library.ucsf.edu/tid/hvk78d00/pdf

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

Ii7 nu2<br />

S p. -lour. Pharm, Sci. 63 (4) 532-35 (1974)<br />

Partition Coefficients of MuorocarUon Aerosol<br />

Propellants in Water, Normal Saline, Cyclohexane,<br />

Chloroform, Human Plasma, and Human Blood<br />

'1^`I^f1^A^2iY'/,,_')`.rIAZl.and 1t'I?d L. C11IOU^<br />

Abstractot'erGtfoncorOhicrosofd[ethmemostaummnnlyused<br />

thwocnrhon propellanes itdc:mromonnnuomrnc[hene, dlchloru-<br />

dilluo me[lione. rnd dichloro:ruatluomuhanrl i^ ^:+[rr, normal<br />

saline ocydobuoor, shlurotao, h- n^ plas^^o. nnd bwoan<br />

distribution, elimination, and pharmacological actirities<br />

of many emnpounds in hmnans and animals has<br />

been cacellently rerie[ved (1). Volatile auorocarbons<br />

such as trichloromono(luoromethane, diehlorndiCfcubtood-e<br />

swdird o- e.idc ron,e of proi,dtaus cnnccnrra- romethane, and clichlorotetratluorocthnnc have been<br />

tions. They -e n4 found to br ir,dcpoud[m[ o: conc.ntra[ion. Na widely used as propellanls in aerosol producta for<br />

salting.ou[ effrct xns seen In -mai ..alme. The narmion eoct0cnt:<br />

in plosm, and blo

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!