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Principles of Microvascular Surgery.

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History<br />

• Zachariah Janssen, 1590 -<br />

invention <strong>of</strong> the compound<br />

microscope.<br />

• Nylen, 1921 - first clinical<br />

application <strong>of</strong> monocular<br />

operating microscope - for<br />

human eardrum surgery.<br />

• Halmgren, 1921 -<br />

stereoscopical microscope<br />

for otolaryngological<br />

procedures.<br />

History<br />

• Perritt, 1950 - microsurgery in clinical<br />

ophthalmology.<br />

• Kurze, 1957 - microsurgery in neurosurgery.<br />

• Jacobson & Suarez, 1960 - microsurgical<br />

anastomosis in carotid arteries (1.4mm) <strong>of</strong><br />

laboratory animals with 100% patency rate.<br />

• Jacobson, 1965 - vessels 1mm in diameter with<br />

100% patency.<br />

• Green, 1966 - used 9-0 nylon suture on rat aortas<br />

(1.3mm) & vena cavas (2.7mm) with patency <strong>of</strong> 37<br />

out <strong>of</strong> 40 animals at 21 days.<br />

2

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