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ALLOPLASTIC MATERIALS IN PLASTIC SURGERY

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Local reaction to silicone<br />

Silicone elastomer-<br />

• May cause capsular contracture.<br />

• Persistent seromas.<br />

Silicone synovitis-<br />

• Infrequent severe synovial inflammatory<br />

response to silicone joint implants.<br />

• Reaction to fragmented particles.<br />

systemic reaction to silicone<br />

• Hematogenous and lymphatic dissemination.<br />

• Human Adjuvant Disease (HAD) – Miyoshi 1973<br />

- stimulation of autoimmune mediated illness after<br />

implantation of foreign body.<br />

- nonspecific connective tissue symptoms (fever,<br />

malasie, arthralgia, arthritis, lymphadenopathy,<br />

ESR, +Rh factor).

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