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ALLOPLASTIC MATERIALS IN PLASTIC SURGERY

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systemic reaction to silicone<br />

Connective tissue disease-<br />

• Controversial – whether silicone and CT<br />

dis. Are related.<br />

• RA, Scleroderma, SLE, Sjogren’s, Mixed<br />

CT dis., etc.<br />

• Scleroderma most commonly associated<br />

with breast implants.<br />

• Epidemiologic studies – no risk of CT dis.<br />

systemic reaction to silicone<br />

Malignancy-<br />

• Silicone injected into mice is carcinogenic.<br />

• No evidence that silicone is carcinogenic in<br />

humans.

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