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December 2004 - Materials Science Institute - University of Oregon

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news<br />

SCAN<br />

BRIEF<br />

POINTS<br />

■ After the success<br />

<strong>of</strong> the privately developed<br />

SpaceShipOne, the X Prize<br />

Foundation and the World<br />

Technology Network announced<br />

plans for prizes to spur<br />

innovation by private fi rms<br />

to solve social problems.<br />

www.wtnxprize.org<br />

■ A detector 1,000 times more<br />

sensitive to motion than existing<br />

sensors relies on two gratings<br />

that deform when one moves<br />

over the other by as little as<br />

10 nanometers. The deformation<br />

visibly affects light<br />

passing through.<br />

Sandia National Laboratory<br />

announcement, September 29, <strong>2004</strong><br />

■ Some scientists and consumer<br />

advocates have called for a<br />

reevaulation <strong>of</strong> studies that led<br />

to lower cholesterol guidelines.<br />

Among other concerns:<br />

eight <strong>of</strong> nine authors <strong>of</strong> the<br />

recommendations had ties to<br />

fi r m s t h a t m a k e c h o l e s t e r o l -<br />

lowering statin drugs.<br />

Center for <strong>Science</strong> in the Public<br />

Interest announcement,<br />

September 23, <strong>2004</strong><br />

■ The technological promise<br />

<strong>of</strong> carbon 60 molecules, or<br />

buckyballs, has been tempered<br />

because they can kill cells.<br />

Attaching hydroxyl, carboxyl and<br />

other simple groups can reduce<br />

toxicity by a factor <strong>of</strong> 10 million.<br />

Nano Letters, October 13, <strong>2004</strong><br />

BEHAVIOR<br />

Stressing Violence<br />

Tempted to knock that smirk <strong>of</strong>f the cashier’s face after<br />

waiting in line for 20 minutes, knowing the parking<br />

meter is about to expire? No wonder: a mutually reinforcing<br />

relationship seems to exist between stress hormones<br />

and the brain pathway that controls violence.<br />

Dutch and Hungarian researchers found that electrically<br />

stimulating this pathway in rats activates the adrenocortical<br />

(“fi ght or fl ight”) stress response. Usually<br />

it takes a confrontation with a rival rat to trigger such<br />

a reaction. Likewise, injecting the rats with the stress<br />

hormone corticosterone prompted them to behave aggressively.<br />

The results reveal a vicious cycle: violent<br />

behavior boosts circulating stress hormones, which<br />

encourages more violence, and so on. The researchers<br />

suggest in the October Behavioral Neuroscience that tinkering with the stress response<br />

may provide a new means to control pathological violence. —Aimee Cunningham<br />

NEUROSCIENCE<br />

Excluding Inclusion Bodies<br />

Researchers studying Huntington’s disease<br />

have debated whether congealed deposits <strong>of</strong><br />

the mutant form <strong>of</strong> the protein huntingtin<br />

cause or protect against the neuron death<br />

that characterizes the neurodegenerative<br />

disorder. The evidence indicting these socalled<br />

inclusion bodies was always circumstantial.<br />

Now <strong>University</strong> <strong>of</strong> California at<br />

San Francisco neurologists have used a robotic<br />

microscope to track neurons up to 10<br />

days after being dosed with a glowing green<br />

form <strong>of</strong> mutant huntingtin. Using tech-<br />

PHYSICS<br />

Wave-Riding Electrons<br />

WOULD YOGA HELP? Stress and violence<br />

form a vicious cycle, as soccer fans in<br />

Copenhagen may have discovered.<br />

niques borrowed from clinical medicine to<br />

evaluate the risk factors for cell death, they<br />

found that dosed cells containing inclusion<br />

bodies are actually less likely to die than<br />

those without them, suggesting that the deposits<br />

sequester the real culprit: free, malformed<br />

huntingtin. The authors note that<br />

Parkinson’s disease causes neurons to form<br />

similar deposits <strong>of</strong> a different protein, hinting<br />

that inclusion bodies may be part <strong>of</strong> neurons’<br />

natural defensive repertoire. Scan the<br />

October 14 Nature for more. —JR Minkel<br />

In so-called plasma accelerators, an extremely intense laser pulse shot into ionized gas<br />

creates a strong, rippling electric fi eld, or “wakefi eld,” which can shove electrons to the<br />

same energies as conventional, kilometers-long accelerators do but in the space <strong>of</strong> a lab<br />

bench. But until recently, electrons in a wakefi eld could be accelerated only to a spectrum<br />

<strong>of</strong> different energies, making precise studies impossible. Now physicists have found ways<br />

to get electrons to ride within a narrow energy range. Groups from the U.K. and France<br />

independently squeezed the range by widening the laser spot, while a U.S. team did so by<br />

shooting a pair <strong>of</strong> laser pulses to guide the wakefi eld from a third pulse. Both methods<br />

enable the electrons to surf the wake from its crest to its trough but no further. Such<br />

machines would have to become at least 10,000 times more powerful to compete with their<br />

bigger brothers, however. Wade into the September 30 Nature for details. —JR Minkel<br />

36 SCIENTIFIC AMERICAN DECEMBER <strong>2004</strong><br />

COPYRIGHT <strong>2004</strong> SCIENTIFIC AMERICAN, INC.<br />

REUTERS/CORBIS

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