stage IIIA

idem. II.
Gilligan D et al Lancet 2007; 369: 1929
Results. I.: 519 pts randomised (S: 261, CT - S: 258) from 70 centres
in UK, Netherlands, Germany and Belgium (61% = clinical stage I,
31% = stage II and 7% = stage III);
- neo - adjuvant chemotherapy feasible (75% of pts had all 3 cycles
of chemotherapy), resulted in good response rate (49%) and downstaging
in 31% of pts and did not alter type or completeness of
surgery (lobectomy: S : 56%, CT - S: 60%, complete resection: S:
80%, CT - S: 82%), with post - operative complications not ↑ in CT - S
group and no impairment of quality of life