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Data Encryption Based On Protein Synthesis - Nguyen Dang Binh

Data Encryption Based On Protein Synthesis - Nguyen Dang Binh

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For For this this process process to to to begin, begin, begin, instructions instructions or<br />

or<br />

blueprints blueprints blueprints are are are required. required. These These instructions instructions instructions could could be<br />

be<br />

found on DNA. Deoxyribonucleic Deoxyribonucleic acid (DNA)<br />

(DNA) is a<br />

nucleic nucleic nucleic acid acid acid that that that contains contains the the genetic genetic genetic instructions<br />

instructions<br />

used used used in in in the the the development development development and and functioning functioning of of all<br />

all<br />

known known known living living living organisms. organisms. The The DNA DNA DNA is is situated situated situated in in in the<br />

the<br />

the<br />

nucleus, nucleus, organized organized into into chromosomes.<br />

chromosomes.<br />

2.1 DNA<br />

The The main main role role of of DNA DNA molecules molecules is the long long-term long<br />

term<br />

storage e of of information information needed needed to to construct other<br />

other<br />

components components components of of cells, cells, cells, such such as as as proteins proteins proteins and and and RNA<br />

RNA<br />

RNA<br />

molecules. molecules. molecules. The The The DNA DNA DNA that that makes makes makes up up up the the the human<br />

human<br />

genome genome genome can can can be be be subdivided subdivided subdivided into into into information information bytes<br />

bytes<br />

bytes<br />

called genes [5]; ; each each gene gene encodes encodes a unique<br />

unique<br />

protein protein that that performs a specialized special<br />

special ized function in in the<br />

the<br />

cell. cell. cell. <strong>On</strong> <strong>On</strong> the the the other other other hand, hand, hand, other other DNA DNA DNA sequences sequences sequences have<br />

have<br />

have<br />

structural structural structural purposes, purposes, or or or are are involved involved in in in regulating regulating regulating the<br />

the<br />

the<br />

use use of of this this genetic genetic information.<br />

information.<br />

In In terms terms of of structure, DNA is a long polymer<br />

polymer<br />

made made made from from repeating repeating repeating units units units called called called nucleotides. nucleotides. nucleotides. In<br />

In<br />

living ving organisms, organisms, DNA DNA does does not not usually usually exist as a<br />

single single single molecule, molecule, but but instead instead as as a a tightly-associated<br />

tightly<br />

tightly associated<br />

pair of molecules. Two wo long strands of the DNA<br />

entwine entwine entwine like like vines, vines, in in in the the shape shape shape of of of a a a double double double helix<br />

helix<br />

helix<br />

[5, [5 8]. . The nucleotide nucleotide repeats, repeats<br />

contain containing both the<br />

segment segment segment of of of the the the backbone backbone backbone of of of the the the molecule, molecule, molecule, which<br />

which<br />

holds holds holds the the the chain chain together, together, together, and and a a a base, base, base, which which which interacts<br />

interacts<br />

interacts<br />

with with with the the the other other other DNA DNA DNA strand strand in in the the the helix. helix. In In general, general, a<br />

a<br />

base base base linked linked linked to to to a a sugar sugar is is called called a a a nucleoside nucleoside nucleoside and and and a<br />

a<br />

a<br />

base base base linked linked to to a a sugar sugar and and and one one or or more more phosphate<br />

groups groups is is called called a a nucleotide.<br />

nucleotide.<br />

The The DNA DNA double double helix helix is is is stabilized stabilized by by hydrogen<br />

bonds bonds bonds between between between the the bases bases attached attached attached to to the the the two<br />

two<br />

two<br />

strands. strands. strands. The The The four four four bases bases found found found in in in DNA DNA DNA are are are adenine<br />

adenine<br />

(abbreviated (abbreviated (abbreviated A), A), A), cytosine cytosine cytosine (C), (C), guanine guanine (G) (G) (G) and<br />

and<br />

and<br />

thymine th (T) ) [5, 8]. 8] Each ach type type of of base on one one strand<br />

forms forms forms a a a bond bond bond with with with just just just one one type type of of of base base on on on the the the other<br />

other<br />

other<br />

strand. strand. strand. This This is is called called complementary complementary complementary base base pairing<br />

[5, 5, 8], 8] , , with with A A bonding bonding only only to to T, T, and and C C bonding bonding only<br />

to to to G. G. This This arrangement arrangement arrangement of of two two two nucleotides nucleotides nucleotides binding<br />

binding<br />

together across the th<br />

e double double helix helix is called a a base base pair<br />

pair<br />

[5, 8]. 8] Due to a weak bond between base pairs, DNA<br />

strands strands strands could could could be be pulled pulled apart apart like like a a a zipper. zipper<br />

zipper<br />

2.2 CODONS<br />

As As previously previously mentioned, mentioned, proteins proteins are are assembled<br />

assembled<br />

from from from amino amino acids acids acids using using using information information encoded encoded encoded in<br />

in<br />

in<br />

genes. genes Each Each protein protein has has has its its its own unique amino acid<br />

sequence sequence sequence that that that is is specified specified by by the the nucleotide<br />

nucleotide<br />

nucleotide<br />

sequence sequence sequence of of of the the the gene gene gene encoding encoding encoding this this this protein. protein. protein. The<br />

The<br />

genetic genetic code code is is a a set set of of three-nucleotide three<br />

three nucleotide sets sets called<br />

called<br />

CODONS and each three-nucleotide three<br />

nucleotide combination<br />

combination<br />

stands for an amino acid, for example AUG AUG stands<br />

for methionine [5, 8].<br />

There are 4 4 bases bases in 3<br />

3-letter combinations; there<br />

are 64 64 possible codons codons ( (4 (<br />

encode the twenty standard amino acids, giving<br />

most amino acids more than one possible codon.<br />

There are also three 'stop' or 'nonsense' codons<br />

signifying the end of the the coding region<br />

are the TAA, TGA and TAG codons.<br />

Figure 2. 2<br />

3 letter combinations; there<br />

combinations). These<br />

These<br />

encode the the twenty twenty standard amino acids, giving<br />

most amino acids more than one possible codon.<br />

There are also three 'stop' or or 'nonsense' 'nonsense' codons<br />

signifying the end of the coding region [5, 8]; ; these<br />

are the TAA, TGA and TAG codons. This is shown in<br />

Figure1 Figure1: : The chemical structure structure of DNA.<br />

Hydrogen bonds bonds bonds are are shown shown as as as dotted dotted lines.<br />

lines.<br />

Figure 2: the combination of 4 base pairs in<br />

codons<br />

2.3 Transcription<br />

DNA transcription transcription is is a a process process process that that involves involves the<br />

the<br />

transcribing of genetic information, information, i.e. i.e. the codons codons of<br />

a gene from from DNA DNA to to RNA<br />

RNA [5]. . Simply stated, in<br />

transcription an an an mRNA mRNA mRNA template, template, template, encoding encoding encoding the<br />

the<br />

the<br />

sequence of of of the the the protein protein protein in in in the the the form form form of of of a a trinucleotide<br />

trinucleotide<br />

code, is is transcribed transcribed from from from the the genome genome to to to provide provide provide a<br />

a<br />

a<br />

template for for for translation. translation. Transcription Transcription Transcription copies copies the<br />

the<br />

template from from from one one one strand strand of of the the the DNA DNA DNA double double double helix,<br />

helix,<br />

helix,<br />

called the template template strand<br />

strand [5, 8].

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