NOVUS BIOLOGICALS ANTIBODIES FOR - BioNova
NOVUS BIOLOGICALS ANTIBODIES FOR - BioNova
NOVUS BIOLOGICALS ANTIBODIES FOR - BioNova
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Alzheimer’s Disease<br />
Alzheimer’s Disease (AD) is a progressive neurodegenerative condition that affects mental capacity, especially<br />
memory and behavior. AD is characterized by two key abnormalities: amyloid plaques and neurofibrillary<br />
tangles. Apolipoprotein E (ApoE) is a lipid transport protein that plays a central role in the pathogenesis of<br />
neurodegeneration in Alzheimer’s disease. [PMID: 14657206] There is also evidence linking Reelin with<br />
neurodegeneration through binding of ApoE receptors and as a mediator of Tau hyperphosphorylation.<br />
[PMID: 15583703]<br />
Related Antibodies<br />
• 160kDa Neurofilament Medium<br />
• Amyloid beta precursor protein<br />
• ApoE<br />
• ApoE4<br />
• ApoER2<br />
ApoE4 (4E4) Antibody<br />
NBP1-49529<br />
Western blot<br />
analysis in<br />
concentrated<br />
supernatants of<br />
CHO cells using<br />
NBP1-49529.<br />
Species: Hu<br />
Applications: WB, ELISA, IP<br />
Customer Reviews<br />
GAPDH Antibody (1D4) NB300-221<br />
Application: Western blot<br />
Sample Tested: Human Hepatoblastoma<br />
Species: Human<br />
Additional Comments: The cultured cells<br />
were harvested, washed and lysed. Extracts<br />
were stored at -20C prior to analysis<br />
• Presenilin 1<br />
• Presenilin 2<br />
• Reelin<br />
• Tau<br />
ApoER2 Antibody<br />
NB100-2216<br />
Species: Hu, Mu, Ch<br />
Applications: WB<br />
Western blot<br />
analysis on<br />
mouse brain<br />
membrane using<br />
NB100-2216.<br />
GAPDH Antibody (NB300-322)<br />
Application: Western blot<br />
Sample Tested: PC3 Whole Cell Lysate<br />
(Human prostate cancer cell)<br />
Species: Human<br />
160kDa Neurofilament Medium<br />
(3H11) Antibody<br />
NB300-134<br />
Immunofluorescent<br />
analysis of adult<br />
neural cells using<br />
NB300-134.<br />
Species: Hu, Mu, Av, Ma<br />
Applications: WB, IF, IHC-P<br />
GAPDH (2D4A7) Antibody<br />
NB300-328<br />
Immunocytochemical<br />
analysis in<br />
HeLa cells using<br />
NB300-328.<br />
Species: Hu, Mu<br />
Applications: WB, ELISA, ICC, IF, IHC-P<br />
GAPDH Antibody (2D4A7) NB300-328<br />
Application: Western blot<br />
Sample Tested: HaCaT whole cell lysate<br />
Sample Pretreatment: UV exposure<br />
Species: Human<br />
Product Citations<br />
[160kDa Neurofilament Medium Antibody NB300-133] Ziv-Polat O, Skaat H, Shahar A, Margel S. Novel<br />
magnetic fibrin hydrogel scaffolds containing thrombin and growth factors conjugated iron oxide nanoparticles<br />
for tissue engineering. Int J Nanomedicine. 2012;7:1259-74. [PMID: 22419873]<br />
[ApoE Antibody NB100-2040] Terwel D, Steffensen KR, Verghese PB, et al. Critical Role of Astroglial<br />
Apolipoprotein E and Liver X Receptor alpha Expression for Microglial Abeta Phagocytosis. J Neurosci. 2011<br />
May 11;31(19):7049-59. [PMID: 21562267]<br />
[ApoE (WUE-4) Antibody NB110-60531] Lee CY, Tse W, Smith JD, Landreth GE. Apolipoprotein E Promotes<br />
ß-Amyloid Trafficking and Degradation by Modulating Microglial Cholesterol Levels. J Biol Chem. 2012 Jan<br />
13;287(3):2032-44. Epub 2011 Nov 30. PubMed [PMID: 22130662].<br />
[GAPDH (1D4) Antibody NB300-221] Hoeffer CA, Sanchez E, Hagerman RJ, Mu Y, Nguyen DV, Wong H,<br />
Whelan AM, Zukin RS, Klann E, Tassone F. Altered mTOR signaling and enhanced CYFIP2 expression levels in<br />
subjects with fragile X syndrome. Genes Brain Behav. 2012 Jan 23. [PMID: 22268788]<br />
[GAPDH Antibody NB300-327] Wang M-E, Chen Y-C, Chen I-S, et al. Curcumin protects against<br />
thioacetamide-induced hepatic fibrosis by attenuating the inflammatory response and inducing apoptosis of<br />
damaged hepatocytes. The Journal of Nutritional Biochemistry. 2012 Jan 3. [PMID: 22221674]<br />
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