ER/PR pharmDx™ Interpretation Manual - Dako

ER/PR Expression in normal tissue
Table 4. Evaluation of Normal Tissue Staining by Dako ER/PR pharmDx TM
Tissue Type (# Tested) Staining Intensity
tissue Element stained ER PR
Adrenal (3) none none
Bone Marrow (3) none none
Breast (3)
Ductal epithelial cells 3,3,3 3,3,3
Brain/Cerebellum (3) none none
Brain/Cerebrum (3) none none
Cervix (3)
basal epithelium 2,3,3 none
stromal cells 1,3,3 2,3,3
Colon (3) none none
Esophagus (3) none none
Heart (3) none none
Kidney (3) none none
Liver (3) none none
Lung (3) none none
Mesothelial Cells (3) none none
Ovary (3)
surface epithelium 0,0,2 0,3,3
stromal cells none 0,3,3
Pancreas (3)
Islet cells* none 1,3,3
Parathyroid (3) none none
Peripheral Nerve (3) none none
Pituitary (3)
Pituicytes 0,1,3 1,2,3*
Prostate (3)
stromal cells 1,1,2 0,2,2
Salivary Gland (3) none none
Skeletal Muscle (3) none none
Skin (3) none none
Small Intestine (3)
Muscularis propria none 0,0,2
Spleen (3) none none
Stomach (3) none none
Testis (3) none none
Thymus (3) none none
Thyroid (3) none none
Tonsil (3) none none
Uterus (3)
Endometrial glands 2,3,3 3,3,3 *
Endometrial stroma 2,2,3 3,3,3
Myometrium 2,3,3 3,3,3
All slides were graded for intensity only on a 0-3 scale.
Nuclear staining.
* Nuclear and cytoplasmic staining.
ER/PR pharmDx Interpretation Manual
ER/PR ExPREssIon
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