B. fragilis
B. fragilis
B. fragilis
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Use of MALDI-TOF MS to distinguish cfiApositive<br />
and cfiA-negative B. <strong>fragilis</strong> strains<br />
(typing of B. <strong>fragilis</strong>)<br />
Carbapenem resistance in B. <strong>fragilis</strong> is due in most cases to the<br />
presence of the cfiA gene and its expression (IS elements are<br />
needed in the promoter region)<br />
This metallo-beta-lactamase confers resistance to all betalactam<br />
antibiotics<br />
Only B. <strong>fragilis</strong> strains belonging in Division II harbor the cfiA<br />
gene<br />
Different studies indicate an increased resistance of B. <strong>fragilis</strong><br />
to carbapenems and an increased frequency of silent harboring<br />
of the gene<br />
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