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Neonatal Cholestasis

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Laboratory Studies<br />

Total and direct bilirubin<br />

LFTs + GGTP<br />

Detects liver cell or bile duct injury<br />

PT/PTT, glucose, albumin<br />

Assessment of biosynthetic capacity of liver<br />

CBC, urine and blood culture<br />

Viral serologies<br />

(TORCH infections + HBsAg, CMV, HIV if indicated)<br />

UA for reducing substances<br />

TFTs<br />

Alpha-1-antitrypsin<br />

Sweat chloride or mutation analysis for CF gene

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