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Glossary of HIV/AIDS-Related Terms - AIDSinfo - National Institutes ...

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A<br />

B<br />

C<br />

D<br />

E<br />

F<br />

G<br />

H<br />

I<br />

J<br />

K<br />

L<br />

M<br />

N<br />

O<br />

P<br />

Q<br />

R<br />

S<br />

T<br />

U<br />

V<br />

W<br />

X<br />

Y<br />

Approved Drug<br />

A drug approved by the Food and Drug Administration (FDA) for sale in<br />

the United States. The extensive FDA drug approval process includes<br />

many steps, including laboratory and animal studies, clinical trials for<br />

safety and efficacy, filing <strong>of</strong> a New Drug Application by the drug<br />

manufacturer, FDA review <strong>of</strong> the application, and FDA approval or<br />

rejection <strong>of</strong> the application.<br />

SEE RELATED TERM(S): Clinical Trial, Food and Drug Administration, New Drug<br />

Application<br />

Area Under the Curve (AUC)<br />

A measure <strong>of</strong> how much drug reaches a person’s bloodstream in a<br />

given period <strong>of</strong> time after a dose is given. The information is useful for<br />

determining dosing and for identifying potential drug interactions.<br />

SEE RELATED TERM(S): Drug Interaction<br />

Arm<br />

Any <strong>of</strong> the treatment groups in a clinical trial.<br />

SEE RELATED TERM(S): Clinical Trial<br />

Arrhythmia<br />

Any irregularity in rhythm or rate <strong>of</strong> the heartbeat.<br />

Arthralgia<br />

Joint pain with additional symptoms such as redness, tenderness to<br />

touch, loss <strong>of</strong> motion, or swelling. Arthralgia is a common symptom <strong>of</strong><br />

<strong>HIV</strong> infection and may be caused by drugs used to treat <strong>HIV</strong> and<br />

opportunistic infections.<br />

Artificial Insemination<br />

ALSO KNOWN AS: Intrauterine Insemination<br />

Aspartate Aminotransferase (AST)<br />

ALSO KNOWN AS: Serum Glutamic-Oxaloacetic Transaminase<br />

An enzyme found especially in heart, muscle, and liver cells. Aspartate<br />

aminotransferase may be measured as part <strong>of</strong> a liver function test.<br />

SEE RELATED TERM(S): Liver Function Test<br />

10 <strong>HIV</strong>/<strong>AIDS</strong> <strong>Glossary</strong>

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