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Table B.25: Red bone marrow in the whole body - Helmholtz ...

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6<br />

all doses presented <strong>in</strong> this catalogue are mean doses averaged over <strong>the</strong><br />

<strong>whole</strong> organ or tissue, not doses only to that part of <strong>the</strong> organ <strong>in</strong>cluded <strong>in</strong><br />

<strong>the</strong> CT slice and irradiated directly.<br />

The number of <strong>in</strong>dividual photon histories followed per s<strong>in</strong>gle CT slice<br />

was 1.000.000; <strong>the</strong> Monte Carlo calculations were performed on an Intel<br />

Hypercube IPSC.<br />

3.2. Human phantoms<br />

The models of <strong>the</strong> human <strong>body</strong> used for <strong>the</strong> calculations were <strong>the</strong> GSF<br />

tomographic paediatric models "BABY" and "CHILD" which were constructed<br />

from <strong>whole</strong> <strong>body</strong> CT data of real patients /10,11/.<br />

Each organ and tissue of <strong>the</strong>se "voxel" models consists of volume elements<br />

(= voxels), derived from <strong>the</strong> CT data. Therefore, <strong>the</strong> location and shape of<br />

<strong>the</strong> organs and tissues is accurately modelled. Special care is given to <strong>the</strong><br />

modell<strong>in</strong>g of <strong>the</strong> red <strong>bone</strong> <strong>marrow</strong> as it is very sensitive to radiation and is<br />

related to leukaemia risk. The relative amount of <strong>bone</strong> <strong>marrow</strong> <strong>in</strong> each<br />

voxel with<strong>in</strong> <strong>the</strong> skeleton can be estimated from <strong>the</strong> CT numbers of <strong>the</strong><br />

respective <strong>bone</strong> pixels (= picture elements). Thus, <strong>the</strong> spatial resolution of<br />

<strong>the</strong> red <strong>bone</strong> <strong>marrow</strong> can be assessed with a resolution as f<strong>in</strong>e as <strong>the</strong> voxel<br />

size, i.e. 2.9 mm 3 for <strong>the</strong> baby and 19 mm 3 for <strong>the</strong> child.<br />

The baby was eight week old when it was scanned and represents, thus,<br />

babies from new-born up to several months. The child was seven years old;<br />

it was, however, slightly small for its age and can be regarded as representative<br />

for <strong>the</strong> age between five and seven years.<br />

Be<strong>in</strong>g reconstructed from CT data, <strong>the</strong> phantoms are primarily made up as<br />

a matrix of rows, columns and slices conta<strong>in</strong><strong>in</strong>g <strong>the</strong> respective volume<br />

elements. Us<strong>in</strong>g <strong>the</strong> appropriate voxel dimensions with respect to width,<br />

depth and height, this matrix can be related to a Cartesian co-ord<strong>in</strong>ate system.<br />

The x-axis is directed across <strong>the</strong> columns from <strong>the</strong> phantoms' right<br />

towards <strong>the</strong>ir left side, <strong>the</strong> y-axis is directed across <strong>the</strong> rows from <strong>the</strong> front<br />

towards <strong>the</strong> back and <strong>the</strong> z-axis across <strong>the</strong> slices from <strong>the</strong> top of <strong>the</strong> head<br />

down to <strong>the</strong> feet. The orig<strong>in</strong> is at <strong>the</strong> upper right frontal corner of this ma-

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