Cell-based kinase assays in HTS Benjamin Bader

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Page 1 and 2: Cell-based kinase assays in HTS Pot
Page 3 and 4: Kinases as drug targets cAbl and Gl
Page 5 and 6: Features of a typical early kinase
Page 7 and 8: General options for cell-based kina
Page 9: TR-FRET systems: HTRF and Lanthascr
Page 13 and 14: Lanthascreen Assay Development BacM
Page 15 and 16: Lanthascreen - virus efficiency 30%
Page 17 and 18: Lanthascreen - optimization • sti
Page 19 and 20: Lanthascreen - inhibitor validation
Page 21 and 22: HTRF - cell lines 18000 Ratio 16000
Page 23 and 24: HTRF - pathway inhibitor validation
Page 25 and 26: Focussed medium throughput screen 2
Page 27 and 28: Focussed medium throughput screen L
Page 29 and 30: Acknowledgements Anja Kretzschmar S

Cell-based kinase assays in HTS Benjamin Bader

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