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Cell-based kinase assays in HTS Benjamin Bader

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Summary & Conclusions<br />

• K<strong>in</strong>ases rema<strong>in</strong> <strong>in</strong>terest<strong>in</strong>g target class <strong>in</strong> pharmaceutical research<br />

• Specific and efficient cell-<strong>based</strong> <strong>k<strong>in</strong>ase</strong> <strong>assays</strong> are essential <strong>in</strong> pharma<br />

research projects<br />

• Homogenous assay systems fit best to Bayers lead discovery platform<br />

• Positive experience at Bayer with EFC-technology, HTRF and<br />

Lanthascreen<br />

• EFC-technology <strong>in</strong>terest<strong>in</strong>g for Tyr-K<strong>in</strong>ase u<strong>HTS</strong><br />

• Lanthascreen technology positioned for secondary test<strong>in</strong>g<br />

• HTRF positioned for u<strong>HTS</strong> and secondary test<strong>in</strong>g<br />

28 HTRF-symposium 2013<br />

281<br />

28

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