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Antibiotic Resistance Threats in the United States, 2013 report

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MULTIDRUG-RESISTANT<br />

PSEUDOMONAS AERUGINOSA<br />

6,700 440<br />

THREAT LEVEL<br />

SERIOUS<br />

This bacteria is a serious concern and requires prompt<br />

and susta<strong>in</strong>ed action to ensure <strong>the</strong> problem does not grow.<br />

MULTIDRUG-RESISTANT<br />

PSEUDOMONAS<br />

INFECTIONS<br />

51,000 PSEUDOMONAS<br />

INFECTIONS<br />

PER YEAR<br />

DEATHS<br />

Pseudomonas aerug<strong>in</strong>osa is a common cause of healthcare-associated <strong>in</strong>fections <strong>in</strong>clud<strong>in</strong>g pneumonia, bloodstream <strong>in</strong>fections, ur<strong>in</strong>ary<br />

tract <strong>in</strong>fections, and surgical site <strong>in</strong>fections.<br />

RESISTANCE OF CONCERN<br />

■■<br />

■■<br />

■■<br />

Some stra<strong>in</strong>s of Pseudomonas aerug<strong>in</strong>osa have been found to be resistant<br />

to nearly all or all antibiotics <strong>in</strong>clud<strong>in</strong>g am<strong>in</strong>oglycosides, cephalospor<strong>in</strong>s,<br />

fluoroqu<strong>in</strong>olones, and carbapenems.<br />

Approximately 8% of all healthcare-associated <strong>in</strong>fections <strong>report</strong>ed to CDC’s<br />

National Healthcare Safety Network are caused by Pseudomonas aerug<strong>in</strong>osa.<br />

About 13% of severe healthcare-associated <strong>in</strong>fections caused by<br />

Pseudomonas aerug<strong>in</strong>osa are multidrug resistant, mean<strong>in</strong>g several classes of<br />

antibiotics no longer cure <strong>the</strong>se <strong>in</strong>fections.<br />

PUBLIC HEALTH THREAT<br />

An estimated 51,000 healthcare-associated Pseudomonas aerug<strong>in</strong>osa <strong>in</strong>fections<br />

occur <strong>in</strong> <strong>the</strong> <strong>United</strong> <strong>States</strong> each year. More than 6,000 (or 13%) of <strong>the</strong>se are<br />

multidrug-resistant, with roughly 400 deaths per year attributed to <strong>the</strong>se<br />

<strong>in</strong>fections.<br />

Multi-drug resistant<br />

Pseudomonas aerug<strong>in</strong>osa<br />

Percentage of all Pseudomonas<br />

aerug<strong>in</strong>osa healthcareassociated<br />

<strong>in</strong>fections that are<br />

multidrug-resistant<br />

Estimated<br />

number of<br />

<strong>in</strong>fections<br />

Estimated<br />

number<br />

of deaths<br />

attributed<br />

13% 6,700 440<br />

For more <strong>in</strong>formation about data methods and references, please see technical appendix.

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