Antibiotic Resistance Threats in the United States, 2013 report

CLINDAMYCIN-RESISTANT GROUP B
STREPTOCOCCUS
FIGHTING THE SPREAD OF RESISTANCE
Doctors should test all pregnant women for GBS at 35–37 weeks of pregnancy and
adhere to the recommended antibiotics during labor and delivery for prevention of earlyonset
disease. Broad efforts to promote appropriate use of antibiotics in outpatient and
inpatient settings will also help minimize the spread of resistance among GBS bacteria.
WHAT CDC IS DOING
CDC, in collaboration with professional associations, has developed evidence-based
Guidelines for the Prevention of Perinatal Group B Streptococcal Disease. These
guidelines discuss diagnosis and management, and recommendations are provided
regarding antibiotic choices and dosing. They also support GBS screening
for all pregnant women at 35–37 weeks of pregnancy and use of antibiotics
during labor and delivery to prevent newborn infection. Through partnerships
between CDC, state health departments, and universities, CDC is tracking GBS
through its Active Bacterial Core surveillance (ABCs). This program monitors
antibiotic resistance and has contributed to the detection of the very first cases in the
U.S. of vancomycin-resistant GBS, as well as tracking of susceptibility trends of other
antibiotics important for treatment of GBS. CDC is promoting appropriate antibiotic use
among outpatient health care providers and the public through its Get Smart: Know
When Antibiotics Work program.
WHAT YOU CAN DO
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Pregnant women should talk to their doctor or nurse about their GBS
status and let them know of any medication allergies during a checkup.
When women get to the hospital or birthing center for delivery, they
should remind their doctor or nurse if they have GBS and if they are
allergic to any medications.
Practice appropriate antibiotic use whenever you see a doctor or are prescribed
an antibiotic for any condition:
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Take antibiotics exactly as the doctor prescribes. Do not skip doses. Complete
the prescribed course of treatment, even when you start feeling better.
Only take antibiotics prescribed for you. Do not share or use leftover
antibiotics.
Do not save antibiotics for the next illness. Discard any leftover medication
once the prescribed course of treatment is completed.
Do not ask for antibiotics when your doctor thinks you do not need them.
Group B strep
continues to
become more
resistant to two
major antibiotics,
leaving those
allergic to first
line drugs in
jeopardy.
Early-onset
group B strep
disease has
declined by
80% since the
introduction of
evidence-based
prevention
strategies.
Proportion of Group B Streptococcus isolates resistant
to erythromycin and clindamycin—
Active Bacterial Core surveillance (ABCs), 2000-2010*
*Most recent data available.
Incidence of Early-Onset Disease Caused by Group B Streptococcus—
Active Bacterial Core surveillance (ABCs), 1989–2010
ACOG = American College of Obstetricians and Gynecologists, AAP = American Academy
of Pediatrics
ONLINE RESOURCES
Group B Strep (GBS)
http://www.cdc.gov/groupbstrep/about/index.html
Active Bacterial Core surveillance (ABCs)
http://www.cdc.gov/abcs/index.html
CS239559-B