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Antibiotic Resistance Threats in the United States, 2013 report

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VANCOMYCIN-RESISTANT<br />

STAPHYLOCOCCUS AUREUS<br />

13<br />

CASES<br />

4<br />

STATES SINCE 2002<br />

IN<br />

THREAT LEVEL<br />

CONCERNING<br />

This bacteria is concern<strong>in</strong>g, and careful monitor<strong>in</strong>g<br />

and prevention action are needed.<br />

SOME STAPHYLOCOCCUS STRAINS ARE RESISTANT TO VANCOMYCIN<br />

LEAVING FEW OR NO TREATMENT OPTIONS<br />

Staphylococcus aureus is a common type of bacteria that is found on <strong>the</strong> sk<strong>in</strong>. Dur<strong>in</strong>g medical procedures when patients require<br />

ca<strong>the</strong>ters or ventilators or undergo surgical procedures, Staphylococcus aureus can enter <strong>the</strong> body and cause <strong>in</strong>fections. When<br />

Staphylococcus aureus becomes resistant to vancomyc<strong>in</strong>, <strong>the</strong>re are few treatment options available because vancomyc<strong>in</strong>-resistant<br />

S. aureus bacteria identified to date were also resistant to methicill<strong>in</strong> and o<strong>the</strong>r classes of antibiotics.<br />

RESISTANCE OF CONCERN<br />

In rare cases, CDC has identified Staphylococcus aureus that is resistant to<br />

vancomyc<strong>in</strong>, <strong>the</strong> antibiotic most frequently used to treat serious S. aureus<br />

<strong>in</strong>fections.<br />

PUBLIC HEALTH THREAT<br />

A total of 13 cases of vancomyc<strong>in</strong>-resistant Staphylococcus aureus (VRSA) have<br />

been identified <strong>in</strong> <strong>the</strong> <strong>United</strong> <strong>States</strong> s<strong>in</strong>ce 2002.<br />

VRSA <strong>in</strong>fection cont<strong>in</strong>ues to be a rare occurrence. A few exist<strong>in</strong>g factors seem to<br />

predispose case patients to VRSA <strong>in</strong>fection, <strong>in</strong>clud<strong>in</strong>g:<br />

■■<br />

■■<br />

■■<br />

Prior MRSA and enterococcal <strong>in</strong>fections or colonization<br />

Underly<strong>in</strong>g conditions (such as chronic sk<strong>in</strong> ulcers and diabetes)<br />

Previous treatment with vancomyc<strong>in</strong><br />

Vancomyc<strong>in</strong>-resistant<br />

Staphylococcus aureus<br />

Number of<br />

cases<br />

Cases per<br />

100,000 U.S.<br />

population<br />

For more <strong>in</strong>formation about data methods and references, please see technical appendix.<br />

Percentage<br />

of all Genus<br />

species cases<br />

<strong>in</strong> U.S.<br />

Number of<br />

deaths<br />

Deaths per<br />

100,000 U.S.<br />

population<br />

13 N/A N/A 0 N/A

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