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uPA for Determining Prognosis in Breast Cancer: NACB Recommendation Lymph node-negative patients with low levels of both uPA have a low risk of disease relapse and thus may be spared from the toxic side effects and costs of adjuvant chemotherapy. Lymph node-negative women with high levels of uPA should be treated with adjuvant chemotherapy. Sturgeon et al, Clin Chem 2008;54:e11-e79
Acknowledgements • HRB • Irish Cancer Society • European Union All the researchers, surgeons, medical oncologists, histopathologists and patients who helped with this work
Page 1 and 2: Breast Cancer Metastasis: Biomarker
Page 3 and 4: Most Important Questions After a Di
Page 5 and 6: Node-Negative Breast Cancer: Treatm
Page 7 and 8: ADJUVANT CHEMOTHERAPY FOR BREAST CA
Page 9 and 10: QUESTION Should most node-negative
Page 11 and 12: Invasion & Metastasis Invasive Carc
Page 13 and 14: uPA in Breast Cancer • We showed
Page 15 and 16: uPA as Prognostic Markers in Breast
Page 17 and 18: LOE for Grading Clinical utility of
Page 19 and 20: Participating laboratories (9 count
Page 21 and 22: STRATIFICATION RANDOMISATION Prospe
Page 23 and 24: uPA in Breast Cancer: Implication o
Page 25: uPA for Determining Prognosis in Br

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