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CHEMOTHERAPY FOR BREAST CANCER: OVERVIEW OF RANDOMISED TRIALS • 18,000 women • 47 trials of chemotherapy vs no chemo Change in 10-yr survival (node-negative patients) •
ADJUVANT CHEMOTHERAPY FOR BREAST CANCER: OVERVIEW OF RANDOMISED TRIALS • 145,000 women • 194 trials of chemotherapy vs no chemo Absolute Improvement in Mortality (%) 5 yr 10 yr 15 yr Women
Page 1 and 2: Breast Cancer Metastasis: Biomarker
Page 3 and 4: Most Important Questions After a Di
Page 5: Node-Negative Breast Cancer: Treatm
Page 9 and 10: QUESTION Should most node-negative
Page 11 and 12: Invasion & Metastasis Invasive Carc
Page 13 and 14: uPA in Breast Cancer • We showed
Page 15 and 16: uPA as Prognostic Markers in Breast
Page 17 and 18: LOE for Grading Clinical utility of
Page 19 and 20: Participating laboratories (9 count
Page 21 and 22: STRATIFICATION RANDOMISATION Prospe
Page 23 and 24: uPA in Breast Cancer: Implication o
Page 25 and 26: uPA for Determining Prognosis in Br
Page 27: Acknowledgements • HRB • Irish

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