Annual Report 2006 - Boehringer Ingelheim

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Financial Highlights Boehringer Ingelheim group of companies Amounts in millions of EUR, unless otherwise indicated 2006 2005 change Net sales 10,574 9,535 11 % by region Europe 31 % 33 % Americas 51 % 48 % Asia, Australasia, Africa 18 % 19 % by business area Human Pharmaceuticals 96 % 96 % Animal Health 4 % 4 % Research and development 1,574 1,360 16 % Personnel costs 2,836 2,671 6 % Average number of employees 38,428 37,406 3 % Operating income 2,140 1,923 11 % Operating income as % of sales 20.2 % 20.2 % Income after taxes 1,729 1,514 14 % Income after taxes as % of sales 16.4 % 15.9 % Shareholders’ equity 5,175 4,609 12 % Return on shareholders’ equity 37.4 % 34.2 % Cash flow 2,317 2,069 12 % Investments in tangible assets 596 532 12 % Depreciation of tangible assets 419 439 -5 % Top 5 products — Prescription Medicines Net sales 2006 in millions of EUR change spiriva® 1,381 45.2 % micardis® 967 33.6 % flomax® 922 27.8 % combivent® 671 19.6 % mobic® 579 -31.8 % Top 5 products — Consumer Health Care Net sales 2006 in millions of EUR change dulcolax® 122.0 6.2 % mucosolvan® 108.3 18.6 % pharmaton® 95.6 8.2 % buscopan® 71.2 19.6 % bisolvon® 67.1 0.4 %
Contents 1 Value Through Innovation 2 The Shareholders’ Perspective 4 Key Aspects of 2006 9 Our Caring Culture 10 “There is help” 14 Our People 18 Caring for our Neighbours 22 Our Environment & Employee Safety 27 Our R & D Drive 28 Targeting tomorrow’s therapies 32 Our R & D Strategy 38 Our Expertise in Landmark Studies 40 From Mind to Man – The R & D Process 42 New Biological Entities (NBE) 43 Biomarker & Pharmacogenetics 45 Serving Patients * 46 “I wake up refreshed ...” 49 Human Pharmaceuticals 60 “My recovery came fast” 78 “Now I know how to keep them under control” 80 From Plant to the Pharmacy – The buscopan® Story 81 Consumer Health Care 84 Our friend Tom 87 Animal Health 91 Our Customer Orientation 92 Biopharmaceuticals – How Innovations are Made 95 Pharmaceuticals Production and Pharma Chemicals 97 Counterfeits – A Real Threat for Patients 99 Group Management Report 115 Consolidated Financial Statements 2006 116 Overview of the Major Consolidated Companies 118 Consolidated Balance Sheet 119 Consolidated Profit and Loss Statement 120 Cash Flow Statement 121 Statement of Changes in Group Equity 122 Notes to the Consolidated Financial Statements 2006 140 Auditor’s Report 142 Glossary Flap Comparison of Balance Sheet / Financial Data 1997–2006 Our friend Tom Every year, about 10 % of all horses suffer from equine colic, a disease that can prove life-threatening. [page 84] “Now I know how to keep them under control” Abdominal pains and cramps, a widespread ailment, is more common in women than in men and can affect people still in their teens. [page 78] * The patient reports are authentic reports which refer to personal experience only. Please acknowledge that other patients may experience different treatment results. Individual treatment schemes have always to be discussed between patient and physician case by case. “There is help“ In Kenya, about 50,000 newborn babies a year are estimated to acquire HIV from their infected mothers. Worldwide UNAIDS talks of 2.3 million cases of AIDS-diseased children. [page 10] Targeting tomorrow’s therapies Focusing on both biopharmaceutical and small molecule drugs, Boehringer Ingelheim has embarked on a major drive to discover and develop new cancer drugs. [page 28] “My recovery came fast” Stroke is a serious disease. It is the third leading cause of death after heart disease and cancer and the most important reason for medical disability. [page 60] “I wake up refreshed ...” Hypertension is not only an unpleasant condition that keeps people from doing what the things they like. It is also a serious cardiovascular risk that can be the precursor to stroke and heart attack. [page 46] please turn over
Page 1: Value through Innovation Annual Rep
Page 5 and 6: The Shareholders’ Perspective Dea
Page 7 and 8: Key Aspects of 2006 2006 was again
Page 9 and 10: This growth was clearly restrained
Page 11 and 12: Shareholders’ Committee Dr Heribe
Page 13 and 14: “There is help” “The woman wh
Page 15 and 16: 1 continued from page 10 A Kenyan m
Page 17 and 18: 1 Our people In pursuing our vision
Page 19 and 20: Company childcare enters new territ
Page 21 and 22: 1 Caring for our neighbours We are
Page 23 and 24: 0 Children from St Margaret Clither
Page 25 and 26: Our environment & employee safety A
Page 27 and 28: thanks to the use of the wood-fired
Page 29 and 30: Our goals We shall continue to inve
Page 31 and 32: Targeting tomorrow’s therapies Th
Page 33 and 34: 0 continued from page 28 “Boehrin
Page 35 and 36: Our R & D strategy Research and dev
Page 37 and 38: Ridgefield, USA Cardiovascular, imm
Page 39 and 40: Vienna, Austria Oncology Boehringer
Page 41 and 42: Our expertise in landmark studies L
Page 43 and 44: From mind to man - the R & D proces
Page 45 and 46: New biological entities (NBE) One o
Page 47 and 48: The development of our businesses W
Page 49: Rin Fujima, Kyoto, Japan, suffers f
Page 52 and 53:
Human Pharmaceuticals Branded presc
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cal exercise capacity and the reduc
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“Like a great round of golf“
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gives patients a better chance of g
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aptivus® was launched in the USA i
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enzymes, such as the HCV serine pro
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Børge Madsen, Copenhagen, Denmark.
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Cardiovascular diseases Despite sig
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actilyse® is the first and only th
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fibrillation in some 40 countries i
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Treatment modalities used to reliev
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HuCAL antibody directed against a c
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hand, the end of exclusivity in Eur
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Generic Prescription Medicines The
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Ben Venue - a world leader in steri
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Mara Lovera, Buenos Aires, Argentin
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Consumer Health Care Our Consumer H
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Switching reinforces the trend towa
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Alexander (left) and Christopher pl
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Animal Health The sound progress of
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located, trained and placed with fi
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Our Customer Orientation Our custom
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On a biopharmaceutical compound’s
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Pharmaceuticals Production Our Phar
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Counterfeits - a real threat for pa
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Group Management Report 2006
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companies lost their patent protect
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To summarise, we see the success of
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Production Production sites belongi
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In the area of HIV/AIDS therapy, we
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only 2 %. The region’s overall ne
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of the cash flow, which rose by EUR
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Report on expected developments The
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Consolidated Financial Statements 2
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C. H. Boehringer Sohn Grundstücksv
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C. H. Boehringer Sohn, Ingelheim Co
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C. H. Boehringer Sohn, Ingelheim St
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The following subsidiaries were exe
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2 Accounting and evaluation methods
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3 Notes to the consolidated balance
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3.3 Financial assets (in millions o
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Pension provisions Boehringer Ingel
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4 Notes to the consolidated profit
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4.7 Holding income (in millions of
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Other mandatory disclosures accordi
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Derivative financial instruments at
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With the following exception, our a
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Product name Active ingredient Indi
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Comparison of Balance Sheets/ Finan
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