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CV Dr. Stefan Westermann 1 Department of Molecular and ... - IMP

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<strong>CV</strong><br />

<strong>Dr</strong>. <strong>Stefan</strong> <strong>Westermann</strong><br />

CURRICULUM VITAE<br />

DR. STEFAN WESTERMANN<br />

PROFESSIONAL ADDRESS<br />

<strong>Department</strong> <strong>of</strong> <strong>Molecular</strong> <strong>and</strong> Cell Biology<br />

University <strong>of</strong> California Berkeley<br />

638 Barker Hall<br />

Berkeley, CA 94720-3202<br />

USA<br />

Tel.: 001 510 643 2010<br />

Fax: 001 510 643 0062<br />

swesterm@uclink.berkeley.edu<br />

PERSONAL DATA Date <strong>of</strong> Birth October 7, 1971<br />

Place <strong>of</strong> Birth Hamm, Germany<br />

Nationality German<br />

EDUCATION<br />

PhD: Biochemistry, University <strong>of</strong> Hannover, Germany, November 2001<br />

Diplom: Biochemistry, University <strong>of</strong> Hannover, Germany, November 1997<br />

PROFESSIONAL EXPERIENCE<br />

From October 2006:<br />

Research Institute <strong>of</strong> <strong>Molecular</strong> Pathology (<strong>IMP</strong>), Vienna<br />

Group leader<br />

<strong>Molecular</strong> Mechanisms <strong>of</strong> Kinetochore Function<br />

University <strong>of</strong> California at Berkeley, Laboratory <strong>of</strong> <strong>Dr</strong>. David <strong>Dr</strong>ubin <strong>and</strong> <strong>Dr</strong>.<br />

Georjana Barnes, <strong>Department</strong> <strong>of</strong> <strong>Molecular</strong> <strong>and</strong> Cell Biology<br />

Postdoctoral Fellow, 8/02- present<br />

Genetic <strong>and</strong> biochemical analysis <strong>of</strong> the Budding Yeast Kinetochore<br />

Max-Planck Institute for Biophysical Chemistry, Goettingen, Germany,<br />

Laboratory <strong>of</strong> <strong>Dr</strong>. Klaus Weber, <strong>Department</strong> <strong>of</strong> Biochemistry<br />

PhD student 11/97 – 7/02<br />

Purification <strong>and</strong> Characterization <strong>of</strong> Tubulin Polyglutamylase<br />

Diploma student 4/97-10/97<br />

Characterization <strong>of</strong> posttranslational Tubulin Modifications<br />

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<strong>CV</strong><br />

<strong>Dr</strong>. <strong>Stefan</strong> <strong>Westermann</strong><br />

HONORS AND AWARDS<br />

PhD awarded summa cum laude<br />

Best Paper Award 2002 Journal <strong>of</strong> Cell Science<br />

Postdoctoral Fellowship German Research Foundation (DFG)<br />

PUBLICATIONS<br />

<strong>Westermann</strong>, S., <strong>Dr</strong>ubin, D.G. <strong>and</strong> Barnes, G. (2006). Structure <strong>and</strong> Function <strong>of</strong> the<br />

Kinetochore. Annu. Rev. Biochemistry, in preparation<br />

<strong>Westermann</strong>, S., Avila-Sakar, A., Wang, H.-W., <strong>Dr</strong>ubin, D.G., Nogales, E. <strong>and</strong> Barnes,<br />

G. (2006) The Dam1 Kinetochore Ring Complex moves processively on depolymerizing<br />

Microtubule ends. Nature404, 565-569.<br />

<strong>Westermann</strong>, S., Avila-Sakar, A., Wang, H.-W., Niederstrasser, H., Wong, J., <strong>Dr</strong>ubin,<br />

D.G., Nogales, E. <strong>and</strong> Barnes, G. (2005) Formation <strong>of</strong> a dynamic kinetochoremicrotubule<br />

Interface through assembly <strong>of</strong> the Dam1 ring complex. Mol. Cell 17, 277-<br />

290.<br />

Comment in Nat Struct Mol Biol. 2005 Mar;12(3):210-2<br />

Curr Biol. 2005 Apr 26;15(8):R299-302<br />

<strong>Westermann</strong> S, Cheeseman, I.M, Anderson, S., Yates III, J.R., <strong>Dr</strong>ubin, D.G. <strong>and</strong> Barnes,<br />

G. (2003). Architecture <strong>of</strong> the Budding Yeast Kinetochore reveals a conserved molecular<br />

core. J. Cell Biol. 163, 215-222.<br />

<strong>Westermann</strong>, S. <strong>and</strong> Weber, K. (2003). Post-translational modifications regulate<br />

microtubule function. Nature Rev. Mol. Cell. Biol. 4, 938-948.<br />

<strong>Westermann</strong>, S. und Weber, K (2002). Identification <strong>of</strong> CfNek, a novel member <strong>of</strong> the<br />

NIMA family <strong>of</strong> cell cycle regulators, as a polypeptide copurifying with tubulin<br />

glutamylation activity in Crithidia. J.Cell.Sci. 115, 5003-5012<br />

Best paper award 2002 J Cell Sci 2003 116: 1155<br />

<strong>Westermann</strong>, S. und Weber, K. (2000). Cloning <strong>and</strong> recombinant expression <strong>of</strong> the La<br />

RNA-binding protein from Trypanosoma brucei. Biochem.Biophys.Acta 1492, 483-487.<br />

2


<strong>CV</strong><br />

<strong>Dr</strong>. <strong>Stefan</strong> <strong>Westermann</strong><br />

<strong>Westermann</strong>, S., Schneider, A., Horn, E.K. und Weber, K. (1999). Isolation <strong>of</strong> Crithidia<br />

tubulin polyglutamylase; binding to microtubules <strong>and</strong> tubulin, <strong>and</strong> glutamylation <strong>of</strong><br />

mammalian brain α- <strong>and</strong> β-tubulins. J.Cell Sci. 112, 2185-2193.<br />

<strong>Westermann</strong>, S., Plessmann, U. und Weber, K. (1999). Synthetic peptides identify the<br />

minimal sequence requirements <strong>of</strong> tubulin polyglutamylase in side chain elongation.<br />

FEBS Lett. 459, 90-94.<br />

Weber, K., Schneider, A., <strong>Westermann</strong>, S., Müller, N. <strong>and</strong> Plessmann, U. (1997). Posttranslational<br />

modifications <strong>of</strong> α- <strong>and</strong> β-tubulin in Giardia lamblia, an ancient eukaryote.<br />

FEBS Lett. 419, 87-91.<br />

Dörk, T., <strong>Westermann</strong>, S., Dittrich, O., Twardowski, M., Karstens, J.H., Schmidtke, <strong>and</strong><br />

Stuhrmann, M.(1997). A frequent polymorphism <strong>of</strong> the gene mutated in ataxia<br />

telangiectasia. Mol. Cell. Probes 11, 71-73<br />

SELECTED TALKS<br />

Cold Spring Harbor Meeting "Yeast Cell Biology", August 12-17, 2003.<br />

<strong>Westermann</strong> S, Cheeseman, I.M, Anderson, S., Yates III, J.R., <strong>Dr</strong>ubin, D.G. <strong>and</strong> Barnes,<br />

G. "<strong>Molecular</strong> Architecture <strong>of</strong> the budding yeast kinetochore"<br />

43rd Annual Meeting American Society for Cell Biology, December 12-17, 2003<br />

<strong>Westermann</strong> S, Cheeseman, I.M, Anderson, S., Yates III, J.R., <strong>Dr</strong>ubin, D.G. <strong>and</strong> Barnes,<br />

G. "Architecture <strong>of</strong> the budding yeast kinetochore reveals a conserved molecular core"<br />

Gordon Research Conference "Plant <strong>and</strong> Fungal Cytoskeleton", August 15-20, 2004<br />

<strong>Westermann</strong> S, <strong>Dr</strong>ubin, D.G., Nogales, E. <strong>and</strong> Barnes G. " The Function <strong>of</strong> the Dam1<br />

complex in spindle integrity <strong>and</strong> chromosome segregation"<br />

Max Planck Institute for Molcular Cell Biology, <strong>Dr</strong>esden, Germany, Invited Seminar,<br />

February 9, 2005<br />

<strong>Westermann</strong> S, <strong>Dr</strong>ubin, D.G., Nogales, E. <strong>and</strong> Barnes G. “Formation <strong>of</strong> a dynamic<br />

Kinetochore-Microtubule Interface in Budding Yeast“.<br />

Third Munich Symposium on Cell Dynamics, Muenchen, Germany October 5-7, 2005,<br />

<strong>Westermann</strong> S, <strong>Dr</strong>ubin, D.G., Nogales, E. <strong>and</strong> Barnes G. " The Kinetochore Ring<br />

Complex moves processively on depolymerizing Microtubule ends"<br />

3


<strong>CV</strong><br />

<strong>Dr</strong>. <strong>Stefan</strong> <strong>Westermann</strong><br />

TEACHING EXPERIENCE<br />

“Biochemistry for Medical Students”, University <strong>of</strong> Hannover, 1994, Teaching<br />

Assistant<br />

“Cell Biology <strong>of</strong> the Cytoskeleton”, Max Planck Institute for Biophysical Chemistry,<br />

2000, International Graduate Student Program, Seminar Series<br />

REFERENCES<br />

Pr<strong>of</strong>essor David <strong>Dr</strong>ubin<br />

University <strong>of</strong> California at Berkeley<br />

Email drubin@socrates.berkeley.edu<br />

Phone: (510) 642-3692<br />

Pr<strong>of</strong>essor Eva Nogales<br />

University <strong>of</strong> California at Berkeley <strong>and</strong> Lawrence Berkeley National Laboratory<br />

Howard Hughes Medical Investigator <strong>and</strong> Associate Pr<strong>of</strong>essor <strong>of</strong> Biochemistry<br />

Email: enogales@lbl.gov<br />

Phone: (510) 642-0557<br />

Pr<strong>of</strong>essor Georjana Barnes<br />

University <strong>of</strong> California at Berkeley<br />

Email: gbarnes@socrates.berkeley.edu<br />

Phone: (510) 642-5962<br />

Pr<strong>of</strong>essor Klaus Weber<br />

<strong>Department</strong> <strong>of</strong> Biochemistry<br />

Max-Planck Institute for Biophysical Chemistry, Goettingen, Germany<br />

Email: <strong>of</strong>fice.weber@mpibpc.gwdg.de<br />

Phone: +49 (0)551 201 1486<br />

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