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immediate volume and may stimulate collagen<br />

synthesis over time—a more subtle result. In contrast,<br />

Botox works by inhibiting small muscles<br />

under the skin from contracting. These muscles<br />

are close to the skin and cause wrinkling or dimples<br />

when they contract. It takes a few days for the<br />

full effect to become apparent, but when it does,<br />

the skin over the muscle becomes smoother, leaving<br />

you looking relaxed and less stressed.<br />

Botox is essentially a toxin that is purified and<br />

reconstituted as a clear, thin liquid. The approved<br />

A COMMON APPROACH IS TO<br />

USE BOTH FILLERS AND BOTOX IN<br />

SOME AREAS, AS THEY CAN WORK<br />

TOGETHER SYNERGISTICALLY<br />

cosmetic formulation has a strong safety profile<br />

when used appropriately. During your initial consultation,<br />

your physician will map out the areas<br />

that concern you. The next step is to identify the<br />

muscles that need to be targeted and the number<br />

of Botox units required to achieve the results you<br />

would like. As mentioned, after the Botox is injected,<br />

it takes several days to work, but then the<br />

effects last for several months. Side effects are few<br />

but can include small bruises from the injection<br />

sites and occasional headaches. (Ironically it can<br />

be used to treat migraines as well, in some instances.)<br />

There are several different types of fillers on<br />

the market. These include temporary fillers that<br />

last three to six months, and then longer-lasting<br />

ones whose effects endure for a year or more.<br />

There are also permanent fillers. These are generally<br />

used in the deeper layers to supplement the<br />

soft issue because if they are placed too close to<br />

the skin they may become visible. As you can see<br />

from this, there are different products and different<br />

strategies to address different problems in the<br />

filler genre and, as with everything, there can be<br />

an overlap of approaches.<br />

The most popular injectable gels at present<br />

are based on hyaluronic acid. Among these are<br />

Restylane, Perlane, and the Juvederm family.<br />

Hyaluronic acid is a naturally occurring substance<br />

in the skin, which holds moisture and provides<br />

some nutrients to the skin. The purported increase<br />

in collagen production is a key in the anti-aging<br />

process, as it reverses the natural one-way trend.<br />

The gels are manufactured in different thicknesses,<br />

so some last longer and are a bit more viscous<br />

than others. Because the gels are more<br />

viscous than Botox, they require larger needles to<br />

insert into the skin. This means there may be more<br />

redness around the injection sites, and also bruis-<br />

ing can be an issue. If you are taking blood thinners<br />

or aspirin products, bruising may be made<br />

worse—something you would need to tell your<br />

physician. The sites may also feel or appear to<br />

have lumps. This means that it is better not to<br />

have these procedures too close to an event or<br />

outing. It is prudent to build in a week or two to be<br />

able to deal with any of these occurrences, should<br />

they arise.<br />

The next level up in terms of duration is the<br />

filler Radiesse, which is based on calcium microspheres<br />

in a water gel. The microspheres are slowly<br />

metabolized by your body, leading to a slow resorbtion.<br />

The formulation is white (the color of calcium).<br />

The gel provides volume and promotes<br />

The improvement is visible...and the results look natural<br />

collagen synthesis. The effect lasts longer than the<br />

hyaluronic acid gels because the resorbtion<br />

process is slower, but it requires deeper injections.<br />

This works well with deeper folds and areas of volume<br />

restoration. As calcium is a biocompatible<br />

substance, there is a very low risk of allergic reactions.<br />

Due to the deeper placement, care has to<br />

be taken to minimize bruising. Again, allowing a<br />

[Continued on page 61]<br />

12 IMAGE Fall 2008

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