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14th European Congress of Clinical Microbiology and Infectious ...

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Poster Sessions Monday, May 3, 2004<br />

P1039 Pharmacokinetics <strong>and</strong> tissue penetration<br />

<strong>of</strong> linezolid in patients with diabetic foot<br />

infection<br />

G. Haase, M. Sass, J. Majcher-Peszynska,<br />

S.C. Müller, R.G. Mundkowski, W. Schareck,<br />

B. Drewelow (Rostock, D)<br />

P1040 Evaluation <strong>of</strong> tigecycline, linezolid,<br />

quinupristin-dalfopristin, arbekacin <strong>and</strong><br />

daptomycin alone <strong>and</strong> in combination with<br />

various antimicrobials against two clinical<br />

strains <strong>of</strong> vancomycin-resistant Staphylococcus<br />

aureus in an in vitro pharmacodynamic model<br />

V. Huang, W. Brown, M. Rybak (Detroit, USA)<br />

P1041 Evaluation <strong>of</strong> cefepime, arbekacin,<br />

daptomycin, gentamicin, tobramycin, <strong>and</strong><br />

tigecycline alone <strong>and</strong> in combination against<br />

methicillin-resistant Staphylococcus aureus in<br />

an in vitro pharmacodynamic infection model<br />

V. Huang, M. Rybak (Detroit, USA)<br />

P1042 Simultaneous methicillin-resistant Staphylococcus<br />

aureus & vancomycin-resistant<br />

Enterococcus faecalis infections in an in vitro<br />

pharmacodynamic model: a comparison<br />

<strong>of</strong> daptomycin, arbekacin, linezolid <strong>and</strong><br />

tigecycline activities<br />

K. Tedesco, M. Rybak (Detroit, USA)<br />

P1043 Pharmacodynamics <strong>of</strong> amoxicillin/clavulanic<br />

acid against Haemophilus influenzae in an in<br />

vitro kinetic model: a comparison <strong>of</strong> different<br />

dosage regimens including a pharmacokinetically<br />

enhanced formulation<br />

E. Löwdin, O. Cars, I. Odenholt (Uppsala, S)<br />

P1044 The comparative antibacterial effect <strong>of</strong><br />

ertapenem <strong>and</strong> ceftriaxone on E. coli studied<br />

in an in vitro pharmacokinetic model <strong>of</strong><br />

infection<br />

K. Bowker, A. Noel, A. MacGowan (Bristol, UK)<br />

P1045 Comparison <strong>of</strong> ertapenem, ampicillin, <strong>and</strong><br />

meropenem against the intracellular forms <strong>of</strong><br />

Listeria monocytogenes in human THP-1<br />

macrophages<br />

S. Lemaire, S. Van de Velde, S. Carryn, F. Van<br />

Bambeke, M.P. Mingeot-Leclercq, P. Tulkens<br />

(Brussels, B)<br />

P1046 Pharmacokinetic-pharmacodynamic modeling<br />

<strong>of</strong> activities <strong>of</strong> cefpodoxime <strong>and</strong> cefixime<br />

based on in vivo tissue concentrations <strong>and</strong> in<br />

vitro kill curves<br />

H. Derendorf, P. Liu, K. R<strong>and</strong>, B. Obermann<br />

(Gainesville, USA; Munich, D)<br />

P1047 Single-dose pharmacokinetics <strong>of</strong> cefodizime<br />

in acutely ill elderly patients<br />

B. Meyer, F. Traunmueller, T. Staudinger,<br />

G. Locker, R. Schmid, F. Thalhammer (Vienna, A)<br />

P1048 Comparative effects <strong>of</strong> ertapenem <strong>and</strong><br />

ceftriaxone on the normal intestinal<br />

micr<strong>of</strong>lora<br />

M.W.R. Pletz, M. Rau, A. de Roux, O. Burkhardt,<br />

M. Kurowski, H. Lode, C.E. Nord<br />

(Berlin, D; Stockholm, S)<br />

P1049 Multiple dose <strong>and</strong> steady-state pharmacokinetics<br />

<strong>of</strong> ertapenem compared to ceftriaxone<br />

in healthy young male <strong>and</strong> female volunteers<br />

M. Rau, M.W.R. Pletz, J. Bulitta, A. de Roux,<br />

G. Schreiber, C.E. Nord, M. Kurowski, G. Kruse,<br />

H. Lode (Berlin, Nuremburg, D; Stockholm, S)<br />

12:00–13:00<br />

Pathogenesis<br />

P1050 Bacterial inhibition <strong>of</strong> phosphatidylcholine<br />

synthesis induces apoptosis in brain cells<br />

J. Zweigner, S. Jackowski, S. Smith,<br />

M. van der Merwe, J. Weber, E. Tuomanen<br />

(Berlin, D; Memphis, USA)<br />

P1051 Bacterial cell-wall derived products induce<br />

a pro-inflammatory <strong>and</strong> pro-fibrogenetic<br />

phenotype in murine hepatic stellate cells<br />

P. Brun, D. Martines, M. Pinzani, G. Palù,<br />

I. Castagliuolo (Padua, I)<br />

P1052 Lipopolysaccharide-induced vascular<br />

endothelial growth factor expression<br />

A.J. Huh, Y.A. Kim, Y.W. Kim, J.S. Yeom,<br />

Y.G. Song, K.H. Chang, J.M. Kim<br />

(Go-yang, Seoul, KOR)<br />

P1053 Antistaphylococcal effect <strong>of</strong> recombinant<br />

human erythropoietin<br />

H. Baskin, Y. Baskin, Y. Dogan, I.H. Bahar<br />

(Izmir, TR)<br />

P1054 Ex vivo release <strong>of</strong> pro-inflammatory cytokines<br />

<strong>of</strong> blood monocytes <strong>of</strong> patients with sepsis:<br />

correlation to the initiation <strong>of</strong> symptoms <strong>and</strong><br />

to monocyte apoptosis<br />

M. Kyriakopoulou, M. Raftogiannis, F. Baziaka,<br />

I. Skiadas, H. Giamarellou, E.J. Giamarellos-<br />

Bourboulis (Athens, GR)<br />

P1055 Adherence factors <strong>of</strong> ocular isolates <strong>of</strong><br />

nontypeable Haemophilus influenzae from<br />

Saudi Arabia<br />

A. Adlan, J.N. Fletcher, A.A. Al-Rajhi, A. Al-Theeb,<br />

A.M. Snelling (Riyadh, SA; Bradford, UK)<br />

P1056 Genetic relationships among nontypable<br />

Haemophilus influenzae isolates presenting<br />

different adhesins pr<strong>of</strong>iles<br />

B. Rybak, E. Augustynowicz, A. Gzyl, G. Gniadek,<br />

J. Slusarczyk, A. Samet (Gdansk, Warsaw, PL)<br />

www.escmid.org/eccmid2004<br />

page 99

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