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CAFEINE CAS : 58-08-2 - UNEP Chemicals

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OECD SIDS CAFFEINE<br />

1. Chemical Name: Caffeine<br />

2. <strong>CAS</strong> No.: <strong>58</strong>-<strong>08</strong>-2<br />

2<br />

SIDS Initial Assessment Report<br />

for<br />

SIAM 14<br />

(Paris, France, March 2002)<br />

3. Sponsor Country: Germany Contact Point:<br />

BMU (Bundesministerium für Umwelt, Naturschutz und<br />

Reaktorsicherheit)<br />

Contact person:<br />

Prof. Dr. Ulrich Schlottmann<br />

Postfach 12 06 29<br />

D- 53048 Bonn-Bad Godesberg<br />

4. Shared Partnership<br />

With:<br />

5. Roles/Responsibilities of<br />

the Partners:<br />

• Name of industry sponsor/<br />

consortium.<br />

BASF AG, Germany;<br />

Bell Flavors & Fragrances, Inc., United States<br />

BASF AG, Germany<br />

Contact person:<br />

Dr. Hubert Lendle<br />

GUP/CL - Z570<br />

D-67056 Ludwigshafen<br />

• Process used. see next page<br />

6. Sponsorship History<br />

• How was the chemical or<br />

category brought into the<br />

SIDS Program?<br />

7. Review Process Prior to<br />

the SIAM:<br />

by ICCA-Initiative<br />

last literature search (update):<br />

24. January 2001 (Human Health): databases medline, toxline; search<br />

profile <strong>CAS</strong>-No. and special search terms 18.04.01 and 02.05.01<br />

(Ecotoxicology): databases CA, biosis; search profile <strong>CAS</strong>-No. and<br />

special search terms<br />

8. Quality Check Process As basis for the SIDS-Dossier the IUCLID was used. All data have<br />

been checked and validated by BUA.<br />

9. Date of Submission: 01. February 2002<br />

10. Comments:<br />

The peer review of BUA in the toxicology section was mainly based on<br />

review articles, including those of the International Agency for Research<br />

on Cancer (IARC), and some others.<br />

Regarding ‘Experience with human exposure: this section of the SIDS<br />

dossier is not adequately worked out according to the formal requests<br />

of OECD manual for investigation of HPV chemicals. However, the<br />

<strong>UNEP</strong> PUBLICATIONS

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