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Oak Ridge Associated Universities 2006 Annual Report

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PROFILE<br />

Scholar’s Immunology Research<br />

Contributes to Homeland Security<br />

From Los Alamos National Laboratory (LANL) to<br />

Lawrence Livermore National Laboratory (LLNL),<br />

Erin Steenblock has gathered research experience<br />

at some of the nation’s top laboratories through<br />

the DHS Scholarship and Fellowship Program,<br />

administered by ORISE.<br />

Competing against nearly 2,500 other<br />

undergraduate applicants, Steenblock was one of<br />

50 winners of a DHS scholarship in 2003. She<br />

spent the summer of 2003 interning at LANL<br />

and the summer of 2004 at LLNL when her<br />

scholarship was extended.<br />

After graduating from the University of Iowa in<br />

2005 with a bachelor’s degree in chemical and<br />

biochemical engineering, Steenblock won a DHS<br />

fellowship. An off-campus internship at a DHSaffiliated<br />

facility is a required component of the<br />

DHS Fellowship Program. The fellowship was<br />

extended for the <strong>2006</strong>-2007 academic year.<br />

Currently a Yale University doctoral student in<br />

biomedical engineering, Steenblock interned in the<br />

summer of <strong>2006</strong> at LLNL and was part of the<br />

Viral Identification and Characterization Initiative<br />

headed by Dr. Bill Colston. The research involved<br />

developing instruments that can detect known and<br />

unknown viruses from environmental or clinical<br />

samples.<br />

Steenblock said her internship enabled her to<br />

gain insight into the myriad ways that science and<br />

technology are used for homeland defense. “I was<br />

surprised by the enormous amount of biological<br />

research that goes into defending our country,”<br />

she said. “Scientists are a big part of homeland<br />

defense, not only in the creation of devices, but in<br />

making decisions on the acceptable use of those<br />

devices.”<br />

When Steenblock interned at LANL in New<br />

Mexico, she was assigned to a team developing a<br />

cell-based biosensor for detecting pathogens.<br />

Image Information:<br />

Steenblock, as an intern at LLNL, prepares solutions in a<br />

protective hood, which provides a clean environment in<br />

which to conduct experiments on DNA. The technology is<br />

important for biodetection of pathogens.<br />

An underlying theme in her research has been the<br />

development of clinical or diagnostic systems<br />

modeled after the way cells or processes function<br />

in the human body or the environment. At Yale, her<br />

research focuses on drug delivery to the immune<br />

system, ultimately seeking ways to stimulate a host’s<br />

response to cancer.<br />

“We hope to develop a cell-free immunotherapy<br />

system that can be easily tailored to a specific<br />

patient’s disease,” Steenblock explained. “This<br />

system also has applications for detection and<br />

screening of a wide range of disease states.”<br />

Originally from Janesville, Wisconsin, Steenblock<br />

encouraged others to apply for the DHS<br />

Scholarship and Fellowship Program, especially<br />

those interested in science and technology as it<br />

relates to homeland defense. She described the<br />

internship experiences of the DHS program<br />

as providing “access to world-class science and<br />

excellent networking opportunities.”<br />

The DHS Scholarship and Fellowship Program is<br />

designed to support, stimulate, and tap into the<br />

intellectual capital in academia to address current<br />

and future homeland security challenges, while at<br />

the same time educating and inspiring the next<br />

generation of scientists and engineers dedicated to<br />

improving homeland security.<br />

51

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