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Oak Ridge Associated Universities 2006 Annual Report

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HIGHLIGHTS<br />

ORISE conducted several peer reviews for EPA in<br />

<strong>2006</strong>, including a toxicological assessment of the<br />

chemical dibutyl phthalate, which is used to make plastics<br />

soft and flexible and is found in products such as shower<br />

curtains and raincoats. Other reviews included a review<br />

of 1,1,1-trichloroethane, which is used as a solvent, and a<br />

review of ceric oxide, an ingredient used to polish glass.<br />

As a part of the peer review process, ORISE identified<br />

and recruited the technical experts to serve as reviewers<br />

and performed analyses to ensure reviewers had no<br />

conflicts of interest.<br />

Scientists, researchers,<br />

DOE officials, and graduate<br />

students in the genomics<br />

field gathered in Bethesda,<br />

Maryland, in February <strong>2006</strong> to<br />

attend the Joint Genomics:<br />

GTL Contractor-Grantee<br />

Workshop IV and Metabolic<br />

Engineering Working Group<br />

Interagency Conference on<br />

Metabolic Engineering <strong>2006</strong>.<br />

The workshop, coordinated<br />

by ORISE and sponsored by<br />

DOE’s Office of Biological<br />

and Environmental Research,<br />

provided an opportunity for the<br />

program investigators to discuss the successes and<br />

challenges of their research. More than 320 people<br />

attended. The Genomics:GTL (GTL) research program<br />

focuses on developing technologies to understand and<br />

use the diverse capabilities of microbes for innovative<br />

solutions to DOE energy and environmental mission<br />

challenges. The genome is an organism’s complete<br />

set of DNA. A strand of DNA, pictured above, contains<br />

a specific sequence, which spells out the exact<br />

instructions required to create a particular organism<br />

with its own unique traits. The ultimate GTL goal is to<br />

generate increasingly accurate mathematical models of<br />

life processes that allow researchers to predict, from an<br />

organism’s genome sequence, its response to varying<br />

environmental conditions.<br />

ORISE is continuing its support of homeland<br />

security research with its collaboration in<br />

the creation of the new U.S. Department of<br />

Homeland Security’s University Affiliate<br />

Centers (UACs). The four designated centers<br />

will conduct research on advanced methods for<br />

information analysis and develop computational<br />

technologies that contribute to securing the<br />

nation. After processing universities’ proposals,<br />

ORISE gathered experts from across the nation<br />

for a peer and merit review panel, which took<br />

place in Washington, D.C., in March. The UACs<br />

were announced in July. Rutgers University, the<br />

University of Southern California, the University<br />

of Illinois at Urbana-Champaign, and the<br />

University of Pittsburgh, and their partners, will<br />

receive a total of $10.2 million from DHS over a<br />

three-year period.<br />

69

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