Applying Biomarker Information To Support Drug Discovery ... - IIR
Applying Biomarker Information To Support Drug Discovery ... - IIR
Applying Biomarker Information To Support Drug Discovery ... - IIR
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D-E-AE Relationship Following S.C. Treatment<br />
PD / Response Rate (%)<br />
100<br />
75<br />
50<br />
25<br />
0<br />
Phase I<br />
135 μg 180 μg<br />
100<br />
75<br />
Phase II<br />
180 μg<br />
135 μg<br />
50<br />
25<br />
ANC< 750<br />
G-III Neutropenia<br />
0<br />
0 100 200 300 0 100 200 300<br />
Dose (μg)<br />
Probability (%)
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