Applying Biomarker Information To Support Drug Discovery ... - IIR
Applying Biomarker Information To Support Drug Discovery ... - IIR
Applying Biomarker Information To Support Drug Discovery ... - IIR
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Apply <strong>Biomarker</strong> <strong>Information</strong> to Define<br />
Candidate Profiles at Early Stage<br />
Develop Long-acting Therapy<br />
• Business<br />
‣Multi-billion dollar market<br />
‣Current situation<br />
• Medically:<br />
‣May help reduce the infection at<br />
dosing site (s.c. qd)<br />
‣Once/week convenience<br />
• PEGSYS success<br />
Target Profile<br />
• Once weekly dosing for<br />
‣Mylosuppressive Neutropenia<br />
‣PBPC<br />
• Efficacy<br />
Equal or better than Filgrastim<br />
• Safety<br />
Comparable safety
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