Contents 2 <strong>Report</strong> of the Supervisory Board 4 Letter from the Managing Board 6 <strong>QIAGEN</strong> — Focusing the Power of Life Sciences 16 Contents — Financial Data <strong>QIAGEN</strong> is the world’s leading provider of innovative technologies for purifying, separating, and handling DNA and RNA — the genetic blueprints of life. Since 1984, <strong>QIAGEN</strong> has successfully developed, produced, and marketed an everincreasing range of proprietary products for academic, industrial, and clinical research. With the sequencing of the entire human genome in 2000, new applications in the life sciences are rapidly emerging. The developing genomics, proteomics, and cellomics markets are fueling applications such as real-time PCR, microarray analysis for gene and drug discovery, DNA- and RNA-based molecular diagnostics, and genetic vaccination and gene therapy. The knowledge that could result — for example, full characterization of mutations in a cancer patient’s tumor — may allow clinicians to develop drug treatments personalized for each patient. This will lead to more effective treatments, as well as reducing the time and expense of developing new drugs by improving our understanding of the mode of drug action. However, these emerging applications share crucial prerequisites — technologies that enable the handling, extraction, and purification of DNA and RNA. <strong>QIAGEN</strong> is uniquely positioned to take full advantage of the wealth of commercial opportunities presented by the life science industry. Already a leader in the life science research market, in <strong>2001</strong> <strong>QIAGEN</strong> strengthened its position in the genomics, proteomics, cellomics, molecular diagnostics, and gene therapy markets through development of innovative products, strategic alliances with key commercial players, and the acquisition of the Sawady group of companies. <strong>2001</strong> was a year of momentum for <strong>QIAGEN</strong> and our traditions of innovation, quality, and service continued to be key factors for growth and success in the Company’s core business — technologies and products for the purification, separation, and handling of nucleic acids.
Financial Highlights Financial Highlights Net Sales 280,000 260,000 Pro Forma Net Income 240,000 220,000 38,000 36,000 200,000 180,000 US$ per share 0.26 Pro Forma Diluted Earnings per Share in US$ thousands 34,000 32,000 30,000 28,000 26,000 24,000 22,000 20,000 18,000 16,000 1996 1997 1998 1999 2000 <strong>2001</strong> 0.24 14,000 0.22 12,000 0.20 10,000 0.18 8,000 0.16 6,000 0.14 4,000 0.12 2,000 0.10 0 0.08 1996 1997 1998 1999 * 2000 ** <strong>2001</strong> *** 0.06 0.04 0.02 0.00 1996 1997 1998 1999 * 2000 ** <strong>2001</strong> *** in US$ thousands 160,000 140,000 120,000 100,000 80,000 60,000 40,000 20,000 0 1 * Excluding the effect of purchased in-process research and development related to the acquisition of Rapigene, Inc. ** Excluding the effect of one-time charges related to the acquisition of Operon Technologies, Inc. *** Excluding the effect of one-time charges as well as expenses related to the acquisition of the Sawady Group
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The Company has elected to adopt SF
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17. LICENSING AGREEMENTS The Compan
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Assets Germany United States Switze
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STATEMENTS OF INCOME FOR THE YEAR E
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7. SHAREHOLDERS’ EQUITY The autho
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OTHER INFORMATION 2. STATUTORY PROF
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1977, Lecturer of Biophysical Chemi
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Since June 27, 1996, the Common Sha
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Corporate Headquarters QIAGEN N.V.
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QIAGEN Investor Relations Dr. Solve