Vol.2, No. 4, 2005 - Rigaku

In This Issue
Newsletter Vol. 2, No. 4,
Winter 2004/5
A word from
our president
A word from our president
Bear with me?I promise there is a point to this story!
Introducing: ZSX Primus II
Anode storage program
Every December my wife and I make the trek from Houston to
Tennessee to visit her family for the holidays. This year we made the
fortunate decision to travel by way of Mississippi and thus avoided a
bad snow/sleet storm that traveled through the country just north of
our drive the first day. We spent the night in Greenwood, MS (home
of the Viking stove company) and in the morning received a copy of
USAToday at our door of the hotel.
ActiveSight Inks Deal with Lexicon
Featured conference
The Rigaku Journal
Introducing: Jupiter 210C
2005 Training Sessions
Introducing: Mini-Z Sulfur Analyzer
Rigaku-EIT News
Personnel changes
Visit us on the web at www.rigaku.com
The food editor of USAToday had written an article about the 20
best dishes in the US. Interestingly enough, one of the top 20 dishes
was tamales from a restaurant in Clarksdale, MS, which was only 40
miles away, however, since I've always found tamales to taste
somewhat like dog food (yes, I sampled dog food once as a kid), I
decided it wasn't worth the trip over the icy back roads. The number
6 dish on the writer's list was the BBQ turkey wings from the A&R
BBQ restaurant on Elvis Presley Blvd in Memphis. Since we were
going to be traveling through Memphis we decided to make the
detour off the highway and surprise her family with one of our
nation's top delicacies.
I fully expected the parking lot of A&R BBQ to be packed with cars
after such national recognition. In fact, as we approached the
restaurant I saw a Sysco food supply truck pull out of the parking lot
and I remarked to my wife that they must have just unloaded a big
batch of turkey wings. I attributed the fact that the parking lot was
almost empty to the icy conditions that still existed from the previous
night's storm.
I entered the restaurant and stood at the counter scanning the
overhead menu. I couldn't find turkey wings listed! When I asked the
clerk for the world famous BBQ turkey wings, she told me that they
took them off the menu because they "didn't move too fast" and
weren't very popular. I asked her if they heard about the article in
USAToday and nobody in the restaurant had. Luckily I had saved the
article and went back out to the car to get it. Everyone in the
restaurant was very impressed (including the cooks) but I had to
settle for Memphis pulled pork to take home to the in-laws.
Point of the story? As a company you don't always know what it is a
customer likes about doing business with you. It is easy to sit in your
office and think you understand what the customers like, but the
only way to really know is to ask the customers. In 2004 we
performed our first full range customer survey and we have used the
results to try and improve what we do. In 2005 we will repeat the
survey to see if we have made some progress. I urge everyone to
respond to the survey this year to improve our feedback on our
business practices and products.
As far as A&R BBQ goes, I have a feeling that they didn't properly
market their product. I would never have considered ordering BBQ
turkey wings if I hadn't read the article in USAToday. They had
developed a unique dish that had stood out to someone whose
occupation it is to comment on food. On the other hand, the writer

also liked tamales, which, as we all know, taste like dog food.
Paul N. Swepston
Jupiter 210C
A major upgrade to the Jupiter 210 product,
known as the Jupiter 210C, was released earlier
this year. The new camera features improvements
in a number of areas, including a higher readout
speed and an additional binning mode. These
significant improvements in electronic performance
combine with a Joules Thompson effect closed
loop cooling system to simplify ease of use and
in-the-field serviceability. An upgrade for most
existing Jupiter 210 owners is also available
providing the same benefits of speed and ease of
use. Please contact your local Rigaku office for
More information.
Calendar of Events
Rigaku will be attending the following conferences
in the winter of 2005:
Protein Crystallography in Drug Discovery,
San Francisco, January 17-18
Introducing
ZSX Primus II
The ZSX Primus
II is the only
sequential
WDXRF system
with the X-ray
tube above the
sample. In this
configuration,
users will never
have to suffer
through
deteriorating
analysis because
of a
contaminated X-
ray path.
Particulate
matter will
never fall into
the analysis
path - no dust,
no pellet pieces,
no powder or
liquids from
ruptured
support films.
Combine this
with the other
features in our 4
kW systemssuch
as
Mapping/Micro
Analysis,
extreme ultralight
element
response,
templates for
any type of
sample analysisand
you have
the complete
laboratory tool,
capable of
handling any
sample, any
sample type, in
any situation.
ActiveSight
inks deal with
Lexicon
ActiveSight, Rigaku's structural biology service company, signed a cocrystallization
service agreement with Lexicon Pharmaceuticals for a
novel human protein target. In the press release, Ron Swanson,
ActiveSight/s CSO, stated, "It is exciting to be able to provide our
structural biology services to Lexicon, a premier drug discovery
company. Accessing structure is a very cost effective way to push a

Australian X-ray Analytical Association
(AXAA), Perth, Australia, February 14-18
PITTCON, Orlando, February 27 - March 4
DGK, Cologne, Germany, February 28 -
March 4
American Chemical Society (ACS), San
Diego, March 13-17
West Coast Protein Crystallography
Workshop (WCPCW), Asilomar, CA, March
20-23
American Physical Society, Los Angeles, CA,
March 21-25
lead development program forward."
ActiveSight will also be expanding their Protein Portfolio in January.
The Protein Portfolio features human target proteins that are
available for rapid co-crystallization studies, with a turn-around time
of under a month. Currently, the Protein Portfolio includes Hsp90, a
cancer target. The new additions will include popular diabetes
targets.
ActiveSight's contract services are centered on lead optimization cocrystallography.
Happy New Year from ActiveSight
Inquiries are welcome: email info@rigaku.com or call Joy Silen at
(858) 455-6870 x105.
>>> Visit our website at www.rigaku.com.
Rigaku instruments in literature
In a paper published in Nature, vol. 432, Nov. 18,
2004, pp. 411-415, Robert T. Batey and his
colleagues at the University of Colorado at
Boulder used an R-AXIS IV++ detector on an RU-
200/Confocal blue optic source to generate an
anomalous signal from a crystal soaked with a Co
hexamine derivative.
>>> Click here to read the abstract
Rigaku
Journal:
Volume 21
No. 2 Nov
2004
Editorial Hideo Toraya (Editor-in-Chief), Ting C. Huang
(Associate Editor-in-Chief)
Practical Aspects of SAS Structure Determination Using
Chromium X-rays John P. Rose, Zhi-Jie Liu, Wolfram Temple,
Lirong Chen, Doowon Lee, M. Gary Newton and Bi-Cheng
Wang
A high-temperature diffraction study of reduction and
reoxidation of nickel oxide Michael D. Dolan and Scott T.
Misture
How Accurate Are Modern Fundamental Parameter Methods?
Michael Mantler and Naoki Kawahara
Analytical Precision and Accuracy in X-ray Fluorescence
Analysis Tomoya Arai
High-resolution X-ray detector for protein structural analyses:
R-AXIS HR
Automatic X-ray single crystal structural analysis system for
small molecule: R-AXIS SPIDER
A new two-dimensional detector for high-speed, high
sensitivity, and non-destructive measurements of
pharmaceutical tablets

Owen, Pritchard and Garman report the results of
their study of temperature characteristics of
crystal storage devices in a CP100 dry shipping
dewar in a paper published in J. Appl. Cryst.
(2004). 37, 1000-1003
>>> Click here to read the abstract
Training Sessions
Rigaku is pleased to announce the following
training sessions for 2005:
XRF:
February 8-10
June 7-9
November 8-10
XRD:
February 16-17 (MiniFlex)
May 11-13 (JADE Software)
September 14-16 (JADE Software)
October 12-13 (MiniFlex)
December 7-8 (MiniFlex)
Macromolecular:
March 30-April 1, 2005
September 21-23, 2005
Featured
conference
Rigaku, Inc. will be exhibiting at the second annual Protein
Crystallography in Drug Discovery conference will be held at the
South San Francisco Conference center (one mile from San Francisco
international airport and 15 minutes from the city center it offers
easy access while also being close to the attractions of downtown
San Francisco) on January 17-18, 2005.
The keynote speaker will be Bernhard Rupp, Group Leader of the
Macromolecular Crystallography and Structural Genomics group at
the Lawrence Livermore National Laboratory, University of California.
He established the high throughput crystallization facility of the TB
Structural Consortium, one of the nine NIH-NIGMS funded Protein
Structure Initiatives (PSI) and is one of many leading authorities
assembled from industry and academia to present the latest cutting
edge developments in the field.
Free passes to the exhibit are available.
Mini-Z Sulfur
Analyzer
Benchtop WD X-ray Fluorescence Spectrometer
The Sulfur Analyzer is
designed to meet the
analysis requirement (less
than 10 ppm) for
petroleum fuels. This XRF
analyzer is based on
testing methods of ISO or
JIS to perform ultra-low
sulfur analysis at ppm
levels, without the pretreatment
of a liquid
reagent adjustment or
dilution by measurement
samples.
Features:
Lower Limit of Detection (LLD): 0.3 ppm
Minimal sample preparation
Automated analysis with 6-sample changer
Based on the testing methods of ISO20884 and ASTM D2622
Easy installation: No cooling water, 100V / 2A power
Rigaku-EIT News
Following the acquisition and integration of what
is now Rigaku-EIT into the Rigaku family, CCD
camera calibration has successfully been
transferred from its previous home at Rigaku's
The Woodlands headquarters to the camera
manufacturing site in Tucson Arizona. With the
acquisition of Rigaku-EIT, Rigaku was already
several steps ahead of the competition as the only
crystallography company to be in direct control of
the development, production and service of the
CCD cameras in Rigaku systems. Now with the
critical calibration step integrated with the
Anode storage
program
The Rigaku customer service department is pleased to announce the
implementation of our Anode Storage Program. This plan allows you
to store your extra anode at Rigaku to maximize the lifetime of your
spare anode.
Uptime of your Rigaku X-ray diffraction system is important to you
and to us at Rigaku. To maximize your uptime, many of you have
purchased a spare anode for your system. Having a spare anode
available allows you the luxury of minimizing your downtime by
immediately installing the replacement anode when it is time to
rebuild the anode in use. Up until now, you were sending the anode
in need of rebuilding to Rigaku, where we would immediately rebuild

manufacturing operation Rigaku has taken a
further step forward in ensuring the highest
performance and standards can continue to be
expected from a Rigaku CCD-based system.
it and return it to you. This replacement anode would then sit on
your shelf until needed.
Experience has shown us that anodes rebuilt (which includes
cleaning, rebuilding, and fine balancing) by Rigaku staff have an
increased expected lifetime. Experience has also shown us that
anodes that sit on a shelf for longer than 3 months may be prone to
early failure. This can be due to a breakdown of the magnetic seal
fluid from non-use or the actual storage conditions. For example,
moisture can cause damage to the bearings and cause early
deterioration of the magnetic seals. In addition, o-ring and rubber
seals tend to harden with age, causing improper seal when put into
use.
The Anode Storage Program works as follows: You send your anode
to the Rigaku customer service department, where it is evaluated.
You would be advised of any work that needs to be done to the
anode to return it to its optimal operating condition. Once a PO is
received, the anode is cleaned, shafts are replaced (as needed) and
the anode is balanced. The anode is then placed into storage under
"ideal" conditions, without seals, magnetic seals, bearings or o-rings.
You would notify us when the anode is required. At that point, new
magnetic seals, bearings and o-rings are installed. The anode is
then re-balanced, checked for vacuum and water leaks and shipped
to you, in prime working condition, within 24 hours of written
notification.
All anodes in the Anode Storage Program will be shipped with a oneyear
warranty, except water seals. This is in contrast to anodes that
are rebuilt and shipped back to the customer to sit on your shelf,
which are warranted from the time the anode ships from Rigaku, not
from the time it is installed.
The goal of the Rigaku Anode Storage Program is to give you
maximum anode lifetime and minimize your costs due to unexpected
down time and premature anode failures.
Subscriber Info
To cancel your subscription, e-mail the
webmaster.
If you have any questions about this new program or would like to
participate in the Rigaku Anode Storage Program, please contact the
Rigaku Customer Service Hotline at 888-362-2324.
Personnel
changes
Jeremy Crawford has been promoted to Senior Installation
Coordinator. He will head up all installations for single crystal, XRF
and XRD. Randy Joyner replaces Thomas Moser as our Installation
Coordinator.
Al Martin, previously our XRF Applications Laboratory Manager, has
now taken over the role of XRF Product Manager for North America.
Al has spent many years working in both the private and government
sectors before coming to Rigaku.
Rigaku is pleased to welcome Dr. Hisayuki Kohno from Rigaku
Industrial Corp (RIC) in Osaka, who will be spending part of the next
12 months with us to better understand the North American GP-XRF
market. Dr. Kohno joined RIC in 1968 and has had a long and
distinguished career with Rigaku.
We are very pleased with the recent growth in our European
business and have recently made some changes to strengthen and
expand our organization. Keith Tame was recently promoted to
Director of European Operations. Tony Sisley steps into Keith's old
position as Service Manager for Europe. The UK office also has a new

administrative assistant, Caroline Duncan, and a new Stock Co-
Ordinator, Sam Trick.
The new contact address for Rigaku's Semiconductor Division is:
infosemi@rigaku.co.jp
North
America:
Europe:
9009 New Trails
Drive
The Woodlands
Texas USA
77381-5209
email:
info@rigaku.com
Tel: (281) 363-
1033
FAX: (281) 364-
3628
Unit B6, Chaucer Business Park
Watery Lane, Kemsing Sevenoaks,
Kent TN15 6QY, England
email: info@rigaku.com
Tel: [44] 1732 763 367
FAX: [44] 1732 763 757