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An Overview, Challenges, and Future Directions - SAMSI

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Experiments Models Connectivity Prediction Summary<br />

Functional Connectivity<br />

Whole-Brain Region to Region Approaches<br />

Calculate the correlation (or partial<br />

correlation) between a all pairs of regions).<br />

∑ T −u<br />

ρ ij = min { t=1 [y i(t + u) − ȳ i ][y j (t) − ȳ j ]<br />

}<br />

u∈U ˆσ i ˆσ j<br />

Requires parcellation of the brain into<br />

regions OR selection of a subset of regions.<br />

May miss important associations due to this<br />

selection process<br />

May select finer or coarser map of regions<br />

depending on objectives<br />

Finer map may prompt the assessment of<br />

whole brain topological properties (graph<br />

methods)<br />

F. D. Bowman (Emory University) <strong>SAMSI</strong>: NDA RTP, NC 36 / 77

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