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An Overview, Challenges, and Future Directions - SAMSI

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Experiments Models Connectivity Prediction Summary<br />

Estimation <strong>and</strong> Prediction<br />

Estimation is performed using MCMC methods (Gibbs)<br />

Prediction:<br />

For region g, we can write<br />

Y g = (Y T g,1 , YT g,2 )T ∼ N ( (µ T g,1 , µT g,2 )T , Ψ g<br />

)<br />

, where Ψg = Σ g ⊗ I Vg .<br />

Then E(Y i ∗ g,2|Y i ∗ g,1) = b i ∗ g , where<br />

b i ∗ g = µ i ∗ g,2 + Ψ T g,12Ψ −1<br />

g,11 (Y i ∗ g,1 − µ i ∗ g,1)<br />

<strong>and</strong> µ i ∗ g = β g + φ g + 1 Vg ⊗ α i ∗ g + 1 Vg ⊗ X i ∗ gv γ gv .<br />

Estimated conditional mean ˆb i ∗ g obtained from inputting the posterior<br />

means of the corresponding parameters<br />

The follow-up brain activity Y i ∗ g,2 is predicted using the estimated<br />

conditional mean ˆb i ∗ g .<br />

F. D. Bowman (Emory University) <strong>SAMSI</strong>: NDA RTP, NC 62 / 77

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