An Overview, Challenges, and Future Directions - SAMSI
An Overview, Challenges, and Future Directions - SAMSI
An Overview, Challenges, and Future Directions - SAMSI
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Experiments Models Connectivity Prediction Summary<br />
Multimodal PD biomarker detection<br />
Suggested links between PD <strong>and</strong> single<br />
genetic, imaging, <strong>and</strong> biologic factors.<br />
Many of these are non-specific or<br />
insensitive.<br />
Single modality biomarkers may not fully<br />
address the complexity of PD.<br />
We regard PD as a complex, systems-level,<br />
multi-dimensional disorder with discrete, but<br />
functionally integrated manifestations.<br />
We are developing methods to define<br />
multimodal PD biomarkers from a massive<br />
number of hypothesis driven <strong>and</strong> exploratory<br />
c<strong>and</strong>idate markers.<br />
F. D. Bowman (Emory University) <strong>SAMSI</strong>: NDA RTP, NC 71 / 77
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