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An Overview, Challenges, and Future Directions - SAMSI

An Overview, Challenges, and Future Directions - SAMSI

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Experiments Models Connectivity Prediction Summary<br />

Methods<br />

High-dimensional Data Methods<br />

Develop statistical models, which pool predictive strength across<br />

multiple data modalities<br />

Proposed statistical techniques<br />

Penalized likelihood approaches:<br />

l p (β, λ) = −l(β) + ∑ k λ kP k (β k )<br />

l(β) = ∑ i [y ilogπ i + (1 − y i )log(1 − π i ]<br />

Variable selection or shrinkage<br />

Novel joint multimodal probability models<br />

Model development, training, testing, <strong>and</strong> validation<br />

F. D. Bowman (Emory University) <strong>SAMSI</strong>: NDA RTP, NC 73 / 77

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