Philips Sonicare FlexCare - Sonicare.com - Sonicare

A Randomized, Single-use Study to
Compare Plaque Removal Ability
of Sonicare FlexCare and Oral-B
Triumph Professional Care 9000
Abstract
The plaque removal ability of a new sonic toothbrush, the Sonicare FlexCare, was compared with the Oral-B
Triumph Professional Care 9000 rotating–oscillating power toothbrush, in a single-use, examiner-blinded, crossover
clinical trial. The Turesky Modified Quigley-Hein (TMQH) plaque index was used for efficacy measurements. A
TMQH score ≥1.8 at screening after 24 hours of oral hygiene abstinence was required for inclusion in the study. At
Visit 1, qualifying subjects received their assigned toothbrush and toothpaste and were instructed to use them twice
daily for 2 minutes during the 7 ± 1-day familiarization phase. Subjects refrained from oral hygiene for 24 hours
before Visit 2. At Visit 2, TMQH scores were appraised before and after a 2-minute supervised brushing episode and
the second test product was issued. Familiarization, plaque accumulation, and clinical examinations were the same
for both study periods. Percent reduction in overall plaque score was the primary efficacy measure. The statistical
data analysis used a linear mixed effects model approach. Comparisons between treatment groups were performed
using F tests. The safety analysis was based on reported adverse events and oral examinations performed at Visits 2
and 3. The study was completed by 91 subjects. The sample’s mean (standard deviation) TMQH score at Visit 1 was
3.45 (0.58). Full-mouth TMQH prebrushing scores were 2.55 (0.76) for FlexCare and 2.81 (0.69) for Triumph.
Brushing reduced the scores by 66.5% (13.0) and 60.1% (13.8) for FlexCare and Triumph, respectively. The mean
percentages were significantly different (P