Perio_III

Periodontics III Summary Notes Enoch Ng
Pregnancy
- Antibiotics may decrease efficacy of birth control pills
Signs of Infection
- SHaRP
- Pain, redness, edema, pus, fistula
- Fever, increased vitals, lymphadenopathy, malaise, increased WBC count
- Penicillin VK 500mg (28tablets)
o 1 tab q6h
• Pen VK take 1hr before or 2hr after meals
• Amox or augmentin take with or w/o food
• Bactericidal (cell wall synthesis)
• Side effects – allergies, pseudomembranous colitis
o
Allergies – 3-10% population
Anaphylactic – 1/7K-25K
Cross-reactivity (cephalosporins) – 3-5%
If pen/amox ineffective within 48-72hr, add in augmentin or metronidazole
• Amox > Pen VK – better absorbed, longer serum half life, may take with food
Peaks at 2h, half life 0.7-1.4hr instead of 30min
- Erythromycin
o Azirthro and erythro – 1hr before or 2hr after meals
o Clarithro – with or w/o food
o Bactericidal – protein synthesis
o Azithro better for perio disease
• Better anaerobic coverage, long serum ½ life, qd only, category B pregnancy
• 250mg BID first day, then qd for 5 days
o Side effects
• Erythro – GI tract and nausea
Antibiotic Principles
- Switch if no response in 48-72h
- Continue 2-3 days after symptoms gone
- Loading dose = double maintenance dose
- If using oral contraceptive, use an additional form of birth control